Cardiac Biomarkers: a Focus on Cardiac Regeneration
Historically, biomarkers have been used in two major ways to maintain and improve better health status: first, for diagnostic purposes, and second, as specific targets to treat various diseases.  A new era in treatment and even cure for the some diseases using reprograming of somatic ce...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2011-12-01
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| Series: | Journal of Tehran University Heart Center |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20047.pdf&manuscript_id=20047 |
| _version_ | 1819230437443108864 |
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| author | Reza Forough Catherine Scarcello Matthew Perkins |
| author_facet | Reza Forough Catherine Scarcello Matthew Perkins |
| author_sort | Reza Forough |
| collection | DOAJ |
| description | Historically, biomarkers have been used in two major ways to maintain and improve better health status: first, for diagnostic purposes, and second, as specific targets to treat various diseases.  A new era in treatment and even cure for the some diseases using reprograming of somatic cells is about to be born. In this approach, scientists are successfully taking human skin cells (previously considered terminally-differentiated cells) and re-programming them into functional cardiac myocytes and other cell types in vitro.  A cell reprograming approach for treatment of cardiovascular diseases will revolutionize the field of medicine and significantly expand the human lifetime. Availability of a comprehensive catalogue for cardiac biomarkers is necessary for developing cell reprograming modalities to treat cardiac diseases, as well as for determining the progress of reprogrammed cells as they become cardiac cells.  In this review, we present a comprehensive survey of the cardiac biomarkers currently known. |
| first_indexed | 2024-12-23T11:29:03Z |
| format | Article |
| id | doaj.art-d2e2cd22f0d746c1b1ec55d6a493c75b |
| institution | Directory Open Access Journal |
| issn | 1735-8620 |
| language | English |
| last_indexed | 2024-12-23T11:29:03Z |
| publishDate | 2011-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Tehran University Heart Center |
| spelling | doaj.art-d2e2cd22f0d746c1b1ec55d6a493c75b2022-12-21T17:48:52ZengTehran University of Medical SciencesJournal of Tehran University Heart Center1735-86202011-12-0164179186Cardiac Biomarkers: a Focus on Cardiac RegenerationReza ForoughCatherine ScarcelloMatthew PerkinsHistorically, biomarkers have been used in two major ways to maintain and improve better health status: first, for diagnostic purposes, and second, as specific targets to treat various diseases.  A new era in treatment and even cure for the some diseases using reprograming of somatic cells is about to be born. In this approach, scientists are successfully taking human skin cells (previously considered terminally-differentiated cells) and re-programming them into functional cardiac myocytes and other cell types in vitro.  A cell reprograming approach for treatment of cardiovascular diseases will revolutionize the field of medicine and significantly expand the human lifetime. Availability of a comprehensive catalogue for cardiac biomarkers is necessary for developing cell reprograming modalities to treat cardiac diseases, as well as for determining the progress of reprogrammed cells as they become cardiac cells.  In this review, we present a comprehensive survey of the cardiac biomarkers currently known.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20047.pdf&manuscript_id=20047Biological markersSomaticStem cellHeartRegeneration |
| spellingShingle | Reza Forough Catherine Scarcello Matthew Perkins Cardiac Biomarkers: a Focus on Cardiac Regeneration Journal of Tehran University Heart Center Biological markers Somatic Stem cell Heart Regeneration |
| title | Cardiac Biomarkers: a Focus on Cardiac Regeneration |
| title_full | Cardiac Biomarkers: a Focus on Cardiac Regeneration |
| title_fullStr | Cardiac Biomarkers: a Focus on Cardiac Regeneration |
| title_full_unstemmed | Cardiac Biomarkers: a Focus on Cardiac Regeneration |
| title_short | Cardiac Biomarkers: a Focus on Cardiac Regeneration |
| title_sort | cardiac biomarkers a focus on cardiac regeneration |
| topic | Biological markers Somatic Stem cell Heart Regeneration |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20047.pdf&manuscript_id=20047 |
| work_keys_str_mv | AT rezaforough cardiacbiomarkersafocusoncardiacregeneration AT catherinescarcello cardiacbiomarkersafocusoncardiacregeneration AT matthewperkins cardiacbiomarkersafocusoncardiacregeneration |