LINC00680 enhances hepatocellular carcinoma stemness behavior and chemoresistance by sponging miR-568 to upregulate AKT3

LINC00680 enhances hepatocellular carcinoma stemness behavior and chemoresistance by sponging miR-568 to upregulate AKT3

Abstract Background Hepatocellular carcinoma (HCC) has an extremely poor prognosis due to the development of chemoresistance, coupled with inherently increased stemness properties. Long non-coding RNAs (LncRNAs) are key regulators for tumor cell stemness and chemosensitivity. Currently the relevance...

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Bibliographic Details
Main Authors: Gege Shu, Huizhao Su, Zhiqian Wang, Shihui Lai, Yan Wang, Xiaomeng Liu, Luo Dai, Yin Bi, Wei Chen, Weiyu Huang, Ziyan Zhou, Songqing He, Hongliang Dai, Bo Tang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatocellular carcinoma
LINC00680
miR-568
AKT3
Stemness
Chemosensitivity
Online Access:https://doi.org/10.1186/s13046-021-01854-5

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