Probiotics and Trained Immunity
The characteristics of innate immunity have recently been investigated in depth in several research articles, and original findings suggest that innate immunity also has a memory capacity, which has been named “trained immunity”. This notion has revolutionized our knowledge of the innate immune resp...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/11/10/1402 |
| _version_ | 1797515246038941696 |
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| author | Naima G. Cortes-Perez Alejandra de Moreno de LeBlanc Jorge G. Gomez-Gutierrez Jean Guy LeBlanc Luis G. Bermúdez-Humarán |
| author_facet | Naima G. Cortes-Perez Alejandra de Moreno de LeBlanc Jorge G. Gomez-Gutierrez Jean Guy LeBlanc Luis G. Bermúdez-Humarán |
| author_sort | Naima G. Cortes-Perez |
| collection | DOAJ |
| description | The characteristics of innate immunity have recently been investigated in depth in several research articles, and original findings suggest that innate immunity also has a memory capacity, which has been named “trained immunity”. This notion has revolutionized our knowledge of the innate immune response. Thus, stimulation of trained immunity represents a therapeutic alternative that is worth exploring. In this context, probiotics, live microorganisms which when administered in adequate amounts confer a health benefit on the host, represent attractive candidates for the stimulation of trained immunity; however, although numerous studies have documented the beneficial proprieties of these microorganisms, their mechanisms of action are not yet fully understood. In this review, we propose to explore the putative connection between probiotics and stimulation of trained immunity. |
| first_indexed | 2024-03-10T06:42:47Z |
| format | Article |
| id | doaj.art-d2e6e498616749afba7660f73b923fad |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T06:42:47Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-d2e6e498616749afba7660f73b923fad2023-11-22T17:32:58ZengMDPI AGBiomolecules2218-273X2021-09-011110140210.3390/biom11101402Probiotics and Trained ImmunityNaima G. Cortes-Perez0Alejandra de Moreno de LeBlanc1Jorge G. Gomez-Gutierrez2Jean Guy LeBlanc3Luis G. Bermúdez-Humarán4Université Paris-Saclay, INRAE, AgroParisTech, UMR 0496, 78350 Jouy-en-Josas, FranceCentro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucuman, Tucuman T4000ILC, ArgentinaDepartment of Child Health, School of Medicine, University of Missouri, Columbia, MO 65201, USACentro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucuman, Tucuman T4000ILC, ArgentinaMicalis Institute, Université Paris-Saclay, INRAE, AgroParisTech, 78350 Jouy-en-Josas, FranceThe characteristics of innate immunity have recently been investigated in depth in several research articles, and original findings suggest that innate immunity also has a memory capacity, which has been named “trained immunity”. This notion has revolutionized our knowledge of the innate immune response. Thus, stimulation of trained immunity represents a therapeutic alternative that is worth exploring. In this context, probiotics, live microorganisms which when administered in adequate amounts confer a health benefit on the host, represent attractive candidates for the stimulation of trained immunity; however, although numerous studies have documented the beneficial proprieties of these microorganisms, their mechanisms of action are not yet fully understood. In this review, we propose to explore the putative connection between probiotics and stimulation of trained immunity.https://www.mdpi.com/2218-273X/11/10/1402probioticstrained immunityimmune responsehuman health |
| spellingShingle | Naima G. Cortes-Perez Alejandra de Moreno de LeBlanc Jorge G. Gomez-Gutierrez Jean Guy LeBlanc Luis G. Bermúdez-Humarán Probiotics and Trained Immunity Biomolecules probiotics trained immunity immune response human health |
| title | Probiotics and Trained Immunity |
| title_full | Probiotics and Trained Immunity |
| title_fullStr | Probiotics and Trained Immunity |
| title_full_unstemmed | Probiotics and Trained Immunity |
| title_short | Probiotics and Trained Immunity |
| title_sort | probiotics and trained immunity |
| topic | probiotics trained immunity immune response human health |
| url | https://www.mdpi.com/2218-273X/11/10/1402 |
| work_keys_str_mv | AT naimagcortesperez probioticsandtrainedimmunity AT alejandrademorenodeleblanc probioticsandtrainedimmunity AT jorgeggomezgutierrez probioticsandtrainedimmunity AT jeanguyleblanc probioticsandtrainedimmunity AT luisgbermudezhumaran probioticsandtrainedimmunity |