Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
Fascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by Fasciola he...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | One Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352771421000550 |
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| author | J.N. Bardales-Valdivia M.D. Bargues C. Hoban-Vergara C. Bardales-Bardales C. Goicochea-Portal H. Bazán-Zurita J. Del Valle-Mendoza P. Ortiz S. Mas-Coma |
| author_facet | J.N. Bardales-Valdivia M.D. Bargues C. Hoban-Vergara C. Bardales-Bardales C. Goicochea-Portal H. Bazán-Zurita J. Del Valle-Mendoza P. Ortiz S. Mas-Coma |
| author_sort | J.N. Bardales-Valdivia |
| collection | DOAJ |
| description | Fascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by Fasciola hepatica, mainly in high altitude areas of Andean regions. The Peruvian Cajamarca area presents the highest human prevalences reported, only lower than those in the Bolivian Altiplano. Sequencing of the complete rDNA ITS-2 allowed for the specific and haplotype classification of lymnaeid snails collected in seasonal field surveys along a transect including 2007–3473 m altitudes. The species Galba truncatula (one haplotype preferentially in higher altitudes) and Pseudosuccinea columella (one haplotype in an isolated population), and the non-transmitting species Lymnaea schirazensis (two haplotypes mainly in lower altitudes) were found. Climatic seasonality proved to influence G. truncatula populations in temporarily dried habitats, whereas L. schirazensis appeared to be more climatologically independent due to its extreme amphibious ecology. Along the southeastern transect from Cajamarca city, G. truncatula and L. schirazensis shared the same site in 7 localities (46.7% of the water collections studied). The detection of G. truncatula in 11 new foci (73.3%), predominantly in northern localities closer to the city, demonstrate that the Cajamarca transmission risk area is markedly wider than previously considered. Lymnaea schirazensis progressively increases its presence when moving away from the city. Results highlight the usefulness of lymnaeid surveys to assess borders of the endemic area and inner distribution of transmission foci. Similar lymnaeid surveys are still in need to be performed in the wide northern and western zones of the Cajamarca city. The coexistence of more than one lymnaeid transmitting species, together with a morphologically indistinguishable non-transmitting species and livestock movements inside the area, conform a complex scenario which poses difficulties for the needed One Health control intervention. |
| first_indexed | 2024-12-22T20:43:32Z |
| format | Article |
| id | doaj.art-d2e7d91ae6124c1fbd2eae474907d143 |
| institution | Directory Open Access Journal |
| issn | 2352-7714 |
| language | English |
| last_indexed | 2024-12-22T20:43:32Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | One Health |
| spelling | doaj.art-d2e7d91ae6124c1fbd2eae474907d1432022-12-21T18:13:16ZengElsevierOne Health2352-77142021-12-0113100265Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, PeruJ.N. Bardales-Valdivia0M.D. Bargues1C. Hoban-Vergara2C. Bardales-Bardales3C. Goicochea-Portal4H. Bazán-Zurita5J. Del Valle-Mendoza6P. Ortiz7S. Mas-Coma8Departamento de Biología y Biotecnología, Facultad de Ciencias de la Salud, Universidad Nacional de Cajamarca, Carretera Baños del Inca km 3,5, Cajamarca, Peru; Facultad de Ciencias Veterinarias, Universidad Nacional de Cajamarca, Carretera Baños del Inca km 3,5, Cajamarca, PeruDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain; Corresponding author.Facultad de Ciencias Veterinarias, Universidad Nacional de Cajamarca, Carretera Baños del Inca km 3,5, Cajamarca, PeruDirección Regional de Agricultura Cajamarca, Gobierno Regional de Cajamarca, Carretera Baños del Inca km 3,5, Cajamarca, PeruDirección Regional de Agricultura Cajamarca, Gobierno Regional de Cajamarca, Carretera Baños del Inca km 3,5, Cajamarca, PeruVice-Rectorado de Investigación, Universidad Privada Antonio Guillermo Urrelo, Jirón José Sabogal No. 913, Cajamarca, PeruEscuela de Medicina, Centro de Investigación e Innovación, Facultad de Ciencias de la Salud, and Laboratorio de Biología Molecular y Celular, Instituto de Investigación Nutricional, Universidad Peruana de Ciencias Aplicadas, Prolongación Primavera No. 2390, Lima, PeruFacultad de Ciencias Veterinarias, Universidad Nacional de Cajamarca, Carretera Baños del Inca km 3,5, Cajamarca, PeruDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, SpainFascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by Fasciola hepatica, mainly in high altitude areas of Andean regions. The Peruvian Cajamarca area presents the highest human prevalences reported, only lower than those in the Bolivian Altiplano. Sequencing of the complete rDNA ITS-2 allowed for the specific and haplotype classification of lymnaeid snails collected in seasonal field surveys along a transect including 2007–3473 m altitudes. The species Galba truncatula (one haplotype preferentially in higher altitudes) and Pseudosuccinea columella (one haplotype in an isolated population), and the non-transmitting species Lymnaea schirazensis (two haplotypes mainly in lower altitudes) were found. Climatic seasonality proved to influence G. truncatula populations in temporarily dried habitats, whereas L. schirazensis appeared to be more climatologically independent due to its extreme amphibious ecology. Along the southeastern transect from Cajamarca city, G. truncatula and L. schirazensis shared the same site in 7 localities (46.7% of the water collections studied). The detection of G. truncatula in 11 new foci (73.3%), predominantly in northern localities closer to the city, demonstrate that the Cajamarca transmission risk area is markedly wider than previously considered. Lymnaea schirazensis progressively increases its presence when moving away from the city. Results highlight the usefulness of lymnaeid surveys to assess borders of the endemic area and inner distribution of transmission foci. Similar lymnaeid surveys are still in need to be performed in the wide northern and western zones of the Cajamarca city. The coexistence of more than one lymnaeid transmitting species, together with a morphologically indistinguishable non-transmitting species and livestock movements inside the area, conform a complex scenario which poses difficulties for the needed One Health control intervention.http://www.sciencedirect.com/science/article/pii/S2352771421000550Human and animal fascioliasisGalba truncatulaLymnaea schirazensisPseudosuccinea columellarDNA ITS-2 sequencingCajamarca hyperendemic area |
| spellingShingle | J.N. Bardales-Valdivia M.D. Bargues C. Hoban-Vergara C. Bardales-Bardales C. Goicochea-Portal H. Bazán-Zurita J. Del Valle-Mendoza P. Ortiz S. Mas-Coma Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru One Health Human and animal fascioliasis Galba truncatula Lymnaea schirazensis Pseudosuccinea columella rDNA ITS-2 sequencing Cajamarca hyperendemic area |
| title | Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru |
| title_full | Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru |
| title_fullStr | Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru |
| title_full_unstemmed | Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru |
| title_short | Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru |
| title_sort | spread of the fascioliasis endemic area assessed by seasonal follow up of rdna its 2 sequenced lymnaeid populations in cajamarca peru |
| topic | Human and animal fascioliasis Galba truncatula Lymnaea schirazensis Pseudosuccinea columella rDNA ITS-2 sequencing Cajamarca hyperendemic area |
| url | http://www.sciencedirect.com/science/article/pii/S2352771421000550 |
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