Cardiovascular and ventilatory acclimatization induced by chronic intermittent hypoxia: A role for the carotid body in the pathophysiology of sleep apnea

Cardiovascular and ventilatory acclimatization induced by chronic intermittent hypoxia: A role for the carotid body in the pathophysiology of sleep apnea

Patients with obstructive sleep apnea (OSA) show augmented ventilatory, sympathetic and cardiovascular responses to hypoxia. The facilitatory effect of chronic intermittent hypoxia (CIH) on the hypoxic ventilatory response has been attributed to a potentiation of the carotid body (CB) chemosensory r...

Full description

Bibliographic Details
Main Authors:	RODRIGO ITURRIAGA, SERGIO REY, RODRIGO DEL RÍO
Format:	Article
Language:	English
Published:	BMC 2005-01-01
Series:	Biological Research
Subjects:	ventilatory acclimatization carotid body chemosensory activity intermittent hypoxia obstructive sleep apnea
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400004

Similar Items

Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia
by: Rodrigo eIturriaga, et al.
Published: (2014-12-01)

Carry-Over Quality of Pre-acclimatization to Altitude Elicited by Intermittent Hypoxia: A Participant-Blinded, Randomized Controlled Trial on Antedated Acclimatization to Altitude
by: Benedikt Treml, et al.
Published: (2020-05-01)

Effect of intermittent normobaric hypoxia exposure on acclimatization to high altitude by air induction
by: Gopinath Bhaumik, et al.
Published: (2021-10-01)

Acclimatization to chronic intermittent hypoxia in mine workers: a challenge to mountain medicine in Chile
by: Jorge G Farias, et al.
Published: (2013-01-01)

Short-Term Sustained Hypoxia Elevates Basal and Hypoxia-Induced Ventilation but Not the Carotid Body Chemoreceptor Activity in Rats
by: Karine C. Flor, et al.
Published: (2018-02-01)

A study of survival strategies for improving acclimatization of lowlanders at high-altitude
by: Poornima Sharma, et al.
Published: (2023-04-01)

Mice and Rats Display Different Ventilatory, Hematological, and Metabolic Features of Acclimatization to Hypoxia
by: Christian Arias-Reyes, et al.
Published: (2021-03-01)

Association of nocturnal intermittent hypoxia with heat shock protein 70 in patients with obstructive sleep apnea: a pilot study
by: Irina M. Madaeva, et al.
Published: (2020-12-01)

Elucidating the combined effect of intermittent hypoxia training and acetazolamide on hypoxia induced hematological and physiological changes
by: Megha A. Nimje, et al.
Published: (2022-01-01)

Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat
by: Agnieszka Swiderska, et al.
Published: (2021-05-01)

Awake Hypercapnic Ventilatory Response in Obstructive Sleep Apnea Syndrome
by: Takashi Sakuma, et al.
Published: (2022-06-01)

Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits
by: S. Leroux, et al.
Published: (2022-09-01)

Global and Transient Effects of Intermittent Hypoxia on Heart Rate Variability Markers: Evaluation Using an Obstructive Sleep Apnea Model
by: Daniel Romero, et al.
Published: (2021-01-01)

Intermittent Hypoxia Mediates Paraspeckle Protein-1 Upregulation in Sleep Apnea
by: Elena Díaz-García, et al.
Published: (2021-08-01)

Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia
by: Katherin Pereyra, et al.
Published: (2023-11-01)

Obstructive Sleep Apnea-Associated Intermittent Hypoxia-Induced Immune Responses in Males, Pregnancies, and Offspring
by: Ruolin Song, et al.
Published: (2024-02-01)

Elevated Monocytic Interleukin-8 Expression under Intermittent Hypoxia Condition and in Obstructive Sleep Apnea Patients
by: Li-Pang Chuang, et al.
Published: (2021-10-01)

Association Between Intermittent Hypoxia and Left Ventricular Remodeling in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome
by: Ming Deng, et al.
Published: (2021-02-01)

Anorexigenic Effects of Intermittent Hypoxia on the Gut—Brain Axis in Sleep Apnea Syndrome
by: Ryogo Shobatake, et al.
Published: (2021-12-01)

Possible Molecular Mechanisms of Hypertension Induced by Sleep Apnea Syndrome/Intermittent Hypoxia
by: Yoshinori Takeda, et al.
Published: (2024-01-01)

Sleep Apnea in Idiopathic Pulmonary Fibrosis: A Molecular Investigation in an Experimental Model of Fibrosis and Intermittent Hypoxia
by: Liasmine Haine, et al.
Published: (2021-09-01)

L-Citrulline Supplementation Reduces Blood Pressure and Myocardial Infarct Size under Chronic Intermittent Hypoxia, a Major Feature of Sleep Apnea Syndrome
by: Bilgehan Ozcan, et al.
Published: (2022-11-01)

The Impact of Intermittent Hypoxia on Metabolism and Cognition
by: Ryogo Shobatake, et al.
Published: (2022-10-01)

Divergent Ventilatory and Blood Pressure Responses are Evident Following Repeated Daily Exposure to Mild Intermittent Hypoxia in Males with OSA and Hypertension
by: Gino S. Panza, et al.
Published: (2022-05-01)

Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea
by: Monique C. Suarez-Giron, et al.
Published: (2018-05-01)

Glucose sensing by carotid body glomus cells: potential implications in disease
by: Lin eGao, et al.
Published: (2014-10-01)

Chronic intermittent hypoxia due to obstructive sleep apnea slightly alters nutritional status: a pre-clinical study
by: Charlotte Breuillard, et al.
Published: (2023-10-01)

Guinea Pig as a Model to Study the Carotid Body Mediated Chronic Intermittent Hypoxia Effects
by: Inmaculada Docio, et al.
Published: (2018-06-01)

The role of ferroptosis in chronic intermittent hypoxia-induced lung injury
by: Jia Chen, et al.
Published: (2022-12-01)

Influence of Intermittent Hypoxia/Hypercapnia on Atherosclerosis, Gut Microbiome, and Metabolome
by: Jin Xue, et al.
Published: (2021-04-01)

Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells
by: Chloe-Anne Martinez, et al.
Published: (2019-01-01)

Glutamatergic Receptors Modulate Normoxic but Not Hypoxic Ventilation and Metabolism in Naked Mole Rats
by: Yvonne A. Dzal, et al.
Published: (2019-02-01)

Commentary: Intermittent Hypoxia Severity in Animal Models of Sleep Apnea
by: Jonathan C. Jun, et al.
Published: (2019-05-01)

Effects of Intermittent Hypoxia on Cytokine Expression Involved in Insulin Resistance
by: Tomoko Uchiyama, et al.
Published: (2021-11-01)

Carotid body, insulin and metabolic diseases: unravelling the links
by: Silvia V Conde, et al.
Published: (2014-10-01)

The efficacy of antihypertensive drugs in chronic intermittent hypoxia conditions
by: Lucilia Neves Diogo, et al.
Published: (2014-09-01)

Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea
by: Lian Li, et al.
Published: (2018-02-01)

Obstructive Sleep Apnea Syndrome In Vitro Model: Controlled Intermittent Hypoxia Stimulation of Human Stem Cells-Derived Cardiomyocytes
by: Danielle Regev, et al.
Published: (2022-09-01)

Intermittent Hypoxia Interferes with Autocrine Effects of GABA on Insulin Secretion in Postnatal Rodents—Implications for Pediatric Obstructive Sleep Apnea
by: Eung-Kwon Pae, et al.
Published: (2022-08-01)

The effect of acute intermittent hypoxia on postprandial triglyceride levels in humans: a randomized crossover trial
by: Renée Morin, et al.
Published: (2021-06-01)