Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study
Purpose: The purpose of this study is to demonstrate and compare the use of optical coherence tomography (OCT) in measuring sagittal depth (SD) and in describing the corneo–scleral junctions with the use of scleral angles, in a population of keratoconics (KC) and of normals (normal). Methods: Fourte...
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| Format: | Article |
| Language: | English |
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Elsevier
2013-07-01
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| Series: | Journal of Optometry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1888429613000204 |
| _version_ | 1819132551449542656 |
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| author | Luigina Sorbara Jyotsna Maram Katrin Mueller |
| author_facet | Luigina Sorbara Jyotsna Maram Katrin Mueller |
| author_sort | Luigina Sorbara |
| collection | DOAJ |
| description | Purpose: The purpose of this study is to demonstrate and compare the use of optical coherence tomography (OCT) in measuring sagittal depth (SD) and in describing the corneo–scleral junctions with the use of scleral angles, in a population of keratoconics (KC) and of normals (normal).
Methods: Fourteen participants (one eye randomly selected) in the normal group and fourteen eyes of nine participants in the keratoconus group were enrolled in the study. Orbscan II (B&L, Rochester) topography was performed to establish eligibility, steep and flat K readings (axes) and HVID. Measurements of the sagittal depth of the cornea and the scleral angles along a particular chord diameter (their HVID and 15 mm) both flat and steep were taken with the use of the on screen measurement tools from the profile view of the cornea of the Visante™ OCT (Carl Zeiss, Dublin, CA).
Results: Data were taken from 14 eyes (11 Females; 3 Males) in the normal group and 14 eyes (5 females; 9 males) in the KC group where either or both eyes were measured. The study participants had a mean age of 33 ± 7yrs (normal) and 40 ± 14yrs (KC). The groups were matched according to HVID: 11.77 ± 0.41 mm (normal) and 11.75 ± 0.35 mm (KC), (p = 0.880). The steep K readings were 53.74 ± 5.98D for the keratoconus eyes as compared to 43.77 ± 1.35D for the control (p < 0.0001). The sagittal depths (±SD) of the keratoconic cornea were significantly different than the normal corneae at their HVID and at 15 mm in the steep meridian only (3.41 ± 0.88 mm versus 2.42 ± 0.09 mm, p = 0.001 and 3.93 ± 0.25 mm versus 3.70 ± 0.16 mm, p = 0.009, respectively). In addition, when the two groups were compared there was no difference in the scleral angles at the HVID's overall (p = 0.490), but there were differences by location (inferior and temporal, p = 0.003). At the 15 mm chord, there was a significant difference between the groups (p = 0.012) overall, but not by location (p = 0.130).
Conclusions: Measurement of the sagittal depth and the corneal-scleral junction angle in the steepest meridian at either the HVID or at 15 mm are two metrics that significantly differentiate normals from keratoconics. |
| first_indexed | 2024-12-22T09:33:12Z |
| format | Article |
| id | doaj.art-d2ea24b4dfcd40c9aaac251c5637297b |
| institution | Directory Open Access Journal |
| issn | 1888-4296 |
| language | English |
| last_indexed | 2024-12-22T09:33:12Z |
| publishDate | 2013-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Optometry |
| spelling | doaj.art-d2ea24b4dfcd40c9aaac251c5637297b2022-12-21T18:30:53ZengElsevierJournal of Optometry1888-42962013-07-016314114610.1016/j.optom.2013.02.002Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot studyLuigina Sorbara0Jyotsna Maram1Katrin Mueller2Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, CanadaDoheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of Southern California, Los Angeles, CA, United StatesAalen University, Aalen, GermanyPurpose: The purpose of this study is to demonstrate and compare the use of optical coherence tomography (OCT) in measuring sagittal depth (SD) and in describing the corneo–scleral junctions with the use of scleral angles, in a population of keratoconics (KC) and of normals (normal). Methods: Fourteen participants (one eye randomly selected) in the normal group and fourteen eyes of nine participants in the keratoconus group were enrolled in the study. Orbscan II (B&L, Rochester) topography was performed to establish eligibility, steep and flat K readings (axes) and HVID. Measurements of the sagittal depth of the cornea and the scleral angles along a particular chord diameter (their HVID and 15 mm) both flat and steep were taken with the use of the on screen measurement tools from the profile view of the cornea of the Visante™ OCT (Carl Zeiss, Dublin, CA). Results: Data were taken from 14 eyes (11 Females; 3 Males) in the normal group and 14 eyes (5 females; 9 males) in the KC group where either or both eyes were measured. The study participants had a mean age of 33 ± 7yrs (normal) and 40 ± 14yrs (KC). The groups were matched according to HVID: 11.77 ± 0.41 mm (normal) and 11.75 ± 0.35 mm (KC), (p = 0.880). The steep K readings were 53.74 ± 5.98D for the keratoconus eyes as compared to 43.77 ± 1.35D for the control (p < 0.0001). The sagittal depths (±SD) of the keratoconic cornea were significantly different than the normal corneae at their HVID and at 15 mm in the steep meridian only (3.41 ± 0.88 mm versus 2.42 ± 0.09 mm, p = 0.001 and 3.93 ± 0.25 mm versus 3.70 ± 0.16 mm, p = 0.009, respectively). In addition, when the two groups were compared there was no difference in the scleral angles at the HVID's overall (p = 0.490), but there were differences by location (inferior and temporal, p = 0.003). At the 15 mm chord, there was a significant difference between the groups (p = 0.012) overall, but not by location (p = 0.130). Conclusions: Measurement of the sagittal depth and the corneal-scleral junction angle in the steepest meridian at either the HVID or at 15 mm are two metrics that significantly differentiate normals from keratoconics.http://www.sciencedirect.com/science/article/pii/S1888429613000204KeratoconusOptical coherence tomographyCorneal/scleral sagittal depthHVIDCorneal curvatureScleral angles |
| spellingShingle | Luigina Sorbara Jyotsna Maram Katrin Mueller Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study Journal of Optometry Keratoconus Optical coherence tomography Corneal/scleral sagittal depth HVID Corneal curvature Scleral angles |
| title | Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study |
| title_full | Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study |
| title_fullStr | Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study |
| title_full_unstemmed | Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study |
| title_short | Use of the Visante™ OCT to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae: Pilot study |
| title_sort | use of the visante™ oct to measure the sagittal depth and scleral shape of keratoconus compared to normal corneae pilot study |
| topic | Keratoconus Optical coherence tomography Corneal/scleral sagittal depth HVID Corneal curvature Scleral angles |
| url | http://www.sciencedirect.com/science/article/pii/S1888429613000204 |
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