Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors
Background: Conventional MR imaging is essential for diagnosis and evaluation of the posterior fossa tumors Objectives: To assess the value of diffusion weighted imaging and apparent diffusion coefficient in making distinction between different histological types of posterior fossa tumors. Typ...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2018-10-01
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| Series: | مجله كليه طب الكندي |
| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/9 |
| _version_ | 1798002044594814976 |
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| author | Lubna Ali Hussain |
| author_facet | Lubna Ali Hussain |
| author_sort | Lubna Ali Hussain |
| collection | DOAJ |
| description |
Background: Conventional MR imaging is essential for diagnosis and evaluation of the posterior fossa tumors Objectives: To assess the value of diffusion weighted imaging and apparent diffusion coefficient in making distinction between different histological types of posterior fossa tumors.
Type of the study: Cross-sectional study.
Methods: Brain MRI and DWI assessed 19 patients (12 female and 7 male) with MRI diagnosis of posterior fossa tumors. absolute ADC values of contrast -enhancing solid tumor region and ADC ratio of solid tumor to ADC of normal -appearing deep White matter were compared with histological diagnosis postoperatively .The mean ADC value and ratio were determined by using a 2-tailed T test. Results: In eight of medulloblastoma ,The mean ADC value was 0.67±0.14x 10-3 mm 2/s and ratio 0.86±0.19 , ependymoma (n=3), ADC value 1.09 ±0.14 x10 -3 mm 2 /s and ratio 1,43±0.13 , pilocytic astrocytoma (n=4) ADC value 1,72 ±0.27x10 -3 mm2/s and ratio 2.19±0.4, brainstem glioma (n=2) with ADC value1.18±0.06 x10-3mm2/s and ratio 1.64±0.08 , haemangioblastoma (n=1) with ADC value1.46x10-1mm2/s and ratio 1.87 , and meningioma with ADC value 0.72x10-3mm2/s and ratio 0.85. ADC values were higher in JPA than in ependymomas and medulloblastoma (P value <o,o5).ADC ratio were also statistically significant difference among these three tumors type .
Conclusion: calculation of apparent diffusion coefficient value in the solid enhancing portion of tumor seems to be reliable for differentiate between medulloblastoma at one end and , juvenile pilocytic astrocytoma (JPA) and ependymoma at other end as the former has ADC of < 1 while other tumors have ADC value of >1.
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| first_indexed | 2024-04-11T11:45:56Z |
| format | Article |
| id | doaj.art-d2f0409923a0470ea7085624ecf13de8 |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-11T11:45:56Z |
| publishDate | 2018-10-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-d2f0409923a0470ea7085624ecf13de82022-12-22T04:25:34ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652018-10-0114110.47723/kcmj.v14i1.9Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa TumorsLubna Ali Hussain Background: Conventional MR imaging is essential for diagnosis and evaluation of the posterior fossa tumors Objectives: To assess the value of diffusion weighted imaging and apparent diffusion coefficient in making distinction between different histological types of posterior fossa tumors. Type of the study: Cross-sectional study. Methods: Brain MRI and DWI assessed 19 patients (12 female and 7 male) with MRI diagnosis of posterior fossa tumors. absolute ADC values of contrast -enhancing solid tumor region and ADC ratio of solid tumor to ADC of normal -appearing deep White matter were compared with histological diagnosis postoperatively .The mean ADC value and ratio were determined by using a 2-tailed T test. Results: In eight of medulloblastoma ,The mean ADC value was 0.67±0.14x 10-3 mm 2/s and ratio 0.86±0.19 , ependymoma (n=3), ADC value 1.09 ±0.14 x10 -3 mm 2 /s and ratio 1,43±0.13 , pilocytic astrocytoma (n=4) ADC value 1,72 ±0.27x10 -3 mm2/s and ratio 2.19±0.4, brainstem glioma (n=2) with ADC value1.18±0.06 x10-3mm2/s and ratio 1.64±0.08 , haemangioblastoma (n=1) with ADC value1.46x10-1mm2/s and ratio 1.87 , and meningioma with ADC value 0.72x10-3mm2/s and ratio 0.85. ADC values were higher in JPA than in ependymomas and medulloblastoma (P value <o,o5).ADC ratio were also statistically significant difference among these three tumors type . Conclusion: calculation of apparent diffusion coefficient value in the solid enhancing portion of tumor seems to be reliable for differentiate between medulloblastoma at one end and , juvenile pilocytic astrocytoma (JPA) and ependymoma at other end as the former has ADC of < 1 while other tumors have ADC value of >1. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/9 |
| spellingShingle | Lubna Ali Hussain Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors مجله كليه طب الكندي |
| title | Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors |
| title_full | Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors |
| title_fullStr | Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors |
| title_full_unstemmed | Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors |
| title_short | Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors |
| title_sort | role of diffusion weighted mr imaging in characterization of posterior fossa tumors |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/9 |
| work_keys_str_mv | AT lubnaalihussain roleofdiffusionweightedmrimagingincharacterizationofposteriorfossatumors |