Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?

Objective: To compare the efficacy of cranial imaging techniques in adult patients with acute febrile encephalopathy. Methods: We enrolled one hundred and two patients presenting to the emergency with fever of shorter than 15-day duration and altered sensorium. All the patients were subjected to rou...

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Main Authors: A Bhalla, V Suri, P Singh, S Varma, NK Khandelwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Acute Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2221618913600025
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author A Bhalla
V Suri
P Singh
S Varma
NK Khandelwal
author_facet A Bhalla
V Suri
P Singh
S Varma
NK Khandelwal
author_sort A Bhalla
collection DOAJ
description Objective: To compare the efficacy of cranial imaging techniques in adult patients with acute febrile encephalopathy. Methods: We enrolled one hundred and two patients presenting to the emergency with fever of shorter than 15-day duration and altered sensorium. All the patients were subjected to routine investigations, detailed cerebrospinal fluid analysis, computerized tomograms (Non contrast followed by contrast enhanced) and Magnetic resonance imaging of the brain. Final diagnosis was reached after considering the clinical, biochemical findings, imaging results and response to therapy. The positive yield of radiological investigations was compared against the final diagnosis. Results: The patients were divided into three groups. Of these patients, 48 had evidence of meningoencephalitis, 22 patients had pyogenic meningitis, and 20 were combined together in others group. In other 12 patients, a definitive diagnosis could not be made. Only 37% patients were detected to have abnormal computerized tomograms and the commonest abnormality was diffuse edema, which failed to point to an etiological diagnosis. Magnetic resonance imaging was abnormal in 62.75% cases and was able to suggest an etiological diagnosis in 100% cases of cerebral venous thrombosis, tubercular meningitis, 95% cases of meningoencephalitis and 45% with meningitis. Conclusions: Magnetic resonance imaging provides better information than computerized tomography in adult patients with acute febrile encephalopathy.
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spelling doaj.art-d2f5a202e8904785a1402b0752570e2a2022-12-21T21:58:28ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892012-01-011171210.1016/S2221-6189(13)60002-5Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?A Bhalla0V Suri1P Singh2S Varma3NK Khandelwal4Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Radio Diagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Radio Diagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaObjective: To compare the efficacy of cranial imaging techniques in adult patients with acute febrile encephalopathy. Methods: We enrolled one hundred and two patients presenting to the emergency with fever of shorter than 15-day duration and altered sensorium. All the patients were subjected to routine investigations, detailed cerebrospinal fluid analysis, computerized tomograms (Non contrast followed by contrast enhanced) and Magnetic resonance imaging of the brain. Final diagnosis was reached after considering the clinical, biochemical findings, imaging results and response to therapy. The positive yield of radiological investigations was compared against the final diagnosis. Results: The patients were divided into three groups. Of these patients, 48 had evidence of meningoencephalitis, 22 patients had pyogenic meningitis, and 20 were combined together in others group. In other 12 patients, a definitive diagnosis could not be made. Only 37% patients were detected to have abnormal computerized tomograms and the commonest abnormality was diffuse edema, which failed to point to an etiological diagnosis. Magnetic resonance imaging was abnormal in 62.75% cases and was able to suggest an etiological diagnosis in 100% cases of cerebral venous thrombosis, tubercular meningitis, 95% cases of meningoencephalitis and 45% with meningitis. Conclusions: Magnetic resonance imaging provides better information than computerized tomography in adult patients with acute febrile encephalopathy.http://www.sciencedirect.com/science/article/pii/S2221618913600025Acute febrile illnessEncephalopathyEncephalitisMeningoencephalitisMagnetic resonance imagingCT scan
spellingShingle A Bhalla
V Suri
P Singh
S Varma
NK Khandelwal
Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?
Journal of Acute Disease
Acute febrile illness
Encephalopathy
Encephalitis
Meningoencephalitis
Magnetic resonance imaging
CT scan
title Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?
title_full Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?
title_fullStr Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?
title_full_unstemmed Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?
title_short Imaging in adult patients with acute febrile encephalopathy: What is better, computerized tomography (CT) or magnetic resonance imaging (MRI)?
title_sort imaging in adult patients with acute febrile encephalopathy what is better computerized tomography ct or magnetic resonance imaging mri
topic Acute febrile illness
Encephalopathy
Encephalitis
Meningoencephalitis
Magnetic resonance imaging
CT scan
url http://www.sciencedirect.com/science/article/pii/S2221618913600025
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