Solution-Phase Combinatorial Chemistry in Lead Discovery

Solution-Phase Combinatorial Chemistry in Lead Discovery

Show other versions (1)

Solution-phase approaches in combinatorial chemistry complement solid-phase approaches and each can be used to advantage in particular circumstances. Solution-phase synthesis of pools of compounds, whilst allowing successful identification of a selection of good lead structures for medicin...

Full description

Bibliographic Details
Main Authors:	Nick Bailey, Stuart Travers, Richard Storer, Andrew T. Merritt, Duncan B. Judd, Michael C. Hawes, Andrea L. Gore, Anthony W. Dean, Martyn J. Deal, Anthony W.J. Cooper, Stephen P. Watson
Format:	Article
Language:	deu
Published:	Swiss Chemical Society 1997-11-01
Series:	CHIMIA
Online Access:	https://www.chimia.ch/chimia/article/view/2914

Similar Items

Solution-Phase Combinatorial Chemistry in Lead Discovery
by: Nick Bailey, et al.
Published: (1997-11-01)

Dynamic combinatorial chemistry : in drug discovery, bioorganic chemistry, and materials science /
by: Miller, Benjamin L.
Published: (2010)

Combinatorial Chemistry: A New Paradigm for Drug Discovery
by: H. Mario Geysen
Published: (1997-11-01)

The impact of combinatorial chemistry on the pharmaceutical drug discovery process
by: Franke, Roland Rolf
Published: (2005)

Scientific Creativity: Discovery and Invention as Combinatorial
by: Dean Keith Simonton
Published: (2021-08-01)

Combinatorial drug discovery in nanoliter droplets
by: Kulesa, Anthony Benjamin, et al.
Published: (2019)

A Candidate for Multitopic Probes for Ligand Discovery in Dynamic Combinatorial Chemistry
by: Keiko Yoneyama, et al.
Published: (2019-06-01)

Combinatorial Chemistry
by: Renato Zenobi
Published: (2000-01-01)

The Effects of Combinatorial Chemistry and Technologies on Drug Discovery and Biotechnology – a Mini Review
by: Seneci Pierfausto, et al.
Published: (2014-12-01)

Support Vector Machines in Combinatorial Chemistry
by: Matthew W B Trotter, et al.
Published: (2001-10-01)

Combinatorial chemistry and technology /
by: Fassina, Giorgio, 1960-, et al.
Published: (2005)

Dynamic combinatorial chemistry /
by: Reek, Joost N. H., et al.
Published: (2010)

Combinatorial discovery of polymers resistant to bacterial attachment
by: Hook, Andrew L., et al.
Published: (2014)

Combinatorial Chemistry at Lead Finding
by: Rudolf Giger
Published: (1997-11-01)

Combinatorial Chemistry at Lead Finding
by: Rudolf Giger
Published: (1997-11-01)

Combinatorial strategies in biology and chemistry /
by: 274945 Beck-Sickinger, Annette, et al.
Published: (2002)

Analytical methods in combinatorial chemistry /
by: Yan, Bing., et al.
Published: (2011)

N-Acylation in combinatorial chemistry
by: Alan R. Katritzky, et al.
Published: (2004-03-01)

A semantic datagrid for combinatorial chemistry.
by: Taylor, K, et al.
Published: (2005)

Analysis and purification methods in combinatorial chemistry /
by: Yan, Bing
Published: (2004)

Combinatorial chemistry : from theory to application /
by: Bannwarth, Willi, et al.
Published: (2006)

Pyrroloindole-Based Dynamic Combinatorial Chemistry
by: Tiberiu-Marius Gianga, et al.
Published: (2020-05-01)

The activated core approach to combinatorial chemistry
by: Pryor, Kent E. (Kent Edward), 1972-
Published: (2014)

Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries
by: Pomplun, Sebastian, et al.
Published: (2022)

Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries
by: Pomplun, Sebastian, et al.
Published: (2022)

Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays
by: Hook, Andrew L., et al.
Published: (2013)

Combinatorial Chemistry on Solid Supports [electronic resource] /
by: Braese, Stefan, et al.
Published: (2007)

Mesofluidic devices for DNA-programmed combinatorial chemistry.
by: Rebecca M Weisinger, et al.
Published: (2012-01-01)

Objective questions in chemistry
by: 211341 Watson, Anthony
Published: (1968)

A chemogenomic HTS for combinatorial drug discovery in glioblastoma
by: Johanssen, T, et al.
Published: (2022)

Combinatorial and high-throughput discovery and optimization of catalysts and materials /
by: Potyrailo, Radislav A., et al.
Published: (2007)

Perturbational Gene-Expression Signatures for Combinatorial Drug Discovery
by: Chen-Tsung Huang, et al.
Published: (2019-05-01)

Recent advances in combinatorial biosynthesis for drug discovery
by: Sun H, et al.
Published: (2015-02-01)

A microfluidic platform for combinatorial experiments
by: Kulesa, Anthony Benjamin
Published: (2019)

New Catalysts and Receptors by Self-Assembly and Combinatorial Chemistry
by: Kay Severin
Published: (2004-04-01)

Structurally divergent dynamic combinatorial chemistry on racemic mixtures
by: Tiberiu-M. Gianga, et al.
Published: (2020-07-01)

The Supramolecular Chemistry of Proteins – Protein Epitope Mimetics Prepared Using Combinatorial Biomimetic Chemistry
by: Luyong Jiang, et al.
Published: (2000-10-01)

Two-phase dynamic combinatorial discovery of a spermine transporter.
by: Pérez-Fernández, R, et al.
Published: (2009)

Discovery of Natural Products With Antifungal Potential Through Combinatorial Synergy
by: Catheryn R. Augostine, et al.
Published: (2022-04-01)

World of scientific discovery /
by: Travers, Bridget
Published: (1994)