Towards an interpretable deep learning model of cancer

Abstract Cancer is a manifestation of dysfunctional cell states. It emerges from an interplay of intrinsic and extrinsic factors that disrupt cellular dynamics, including genetic and epigenetic alterations, as well as the tumor microenvironment. This complexity can make it challenging to infer molec...

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Bibliographic Details
Main Authors: Avlant Nilsson, Nikolaos Meimetis, Douglas A. Lauffenburger
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00822-y