Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series
Introduction: Rhabdomyosarcoma, the most common malignant mesenchymal tumour in children, primarily affects the urogenitals. In Europe, the prognosis of the localised forms is excellent, whereas in sub-saharan Africa, it is reserved. This observation study aimed to report the diagnostic, therapeutic...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Journal of Pediatric Surgery Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213576623000593 |
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| author | Kokoé Agblévi Midékor Gonébo Moufidath Sounkéré Soro Rébécca Bonny Obro Amenan Kan Sophie Kouassi Dria Sigué Jean Jaurès Ouattara Yapi Landry Aké Nicolas Moh Ello |
| author_facet | Kokoé Agblévi Midékor Gonébo Moufidath Sounkéré Soro Rébécca Bonny Obro Amenan Kan Sophie Kouassi Dria Sigué Jean Jaurès Ouattara Yapi Landry Aké Nicolas Moh Ello |
| author_sort | Kokoé Agblévi Midékor Gonébo |
| collection | DOAJ |
| description | Introduction: Rhabdomyosarcoma, the most common malignant mesenchymal tumour in children, primarily affects the urogenitals. In Europe, the prognosis of the localised forms is excellent, whereas in sub-saharan Africa, it is reserved. This observation study aimed to report the diagnostic, therapeutic, evolutionary, and prognostic aspects of rhabdomyosarcoma. Case presentation: This was a series of six observations in four boys and two girls, all of whom had no significant medical history. An abdominal mass in two patients and a pelvic mass in the others evolved over 10 days to 4 months. All localizations were complicated by signs of compression: urinary for the pelvic and digestive for the abdomen. CT tomography revealed urogenital localisation in four patients and abdominal localisation in one patient. A histological examination revealed embryonic rhabdomyosarcoma in all patients. Chemotherapy was neoadjuvant in five patients and postoperative in one patient. Immediate tumour resection was performed in one patient. All patients died: five during chemotherapy and one following recurrence after 1 year of remission. Conclusion: The prognosis of rhabdomyosarcomas is linked to delays in consultation, tumour size, histological type, and therapeutic difficulties. Adequate management of this condition requires multidisciplinary consultation. |
| first_indexed | 2024-04-09T13:22:23Z |
| format | Article |
| id | doaj.art-d2fb68c2c1234a998a46a82b61a572b0 |
| institution | Directory Open Access Journal |
| issn | 2213-5766 |
| language | English |
| last_indexed | 2024-04-09T13:22:23Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pediatric Surgery Case Reports |
| spelling | doaj.art-d2fb68c2c1234a998a46a82b61a572b02023-05-11T04:23:54ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662023-06-0193102633Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case seriesKokoé Agblévi Midékor Gonébo0Moufidath Sounkéré Soro1Rébécca Bonny Obro2Amenan Kan Sophie Kouassi Dria3Sigué Jean Jaurès Ouattara4Yapi Landry Aké5Nicolas Moh Ello6Corresponding author. Pediatric Surgery Department of Cocody University Hospital, 22 BP 1178 Abidjan 22, Abidjan, Cote d’Ivoire.; Pediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoirePediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoirePediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoirePediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoirePediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoirePediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoirePediatric Surgery Department of Cocody University Hospital, Abidjan, Cote d’IvoireIntroduction: Rhabdomyosarcoma, the most common malignant mesenchymal tumour in children, primarily affects the urogenitals. In Europe, the prognosis of the localised forms is excellent, whereas in sub-saharan Africa, it is reserved. This observation study aimed to report the diagnostic, therapeutic, evolutionary, and prognostic aspects of rhabdomyosarcoma. Case presentation: This was a series of six observations in four boys and two girls, all of whom had no significant medical history. An abdominal mass in two patients and a pelvic mass in the others evolved over 10 days to 4 months. All localizations were complicated by signs of compression: urinary for the pelvic and digestive for the abdomen. CT tomography revealed urogenital localisation in four patients and abdominal localisation in one patient. A histological examination revealed embryonic rhabdomyosarcoma in all patients. Chemotherapy was neoadjuvant in five patients and postoperative in one patient. Immediate tumour resection was performed in one patient. All patients died: five during chemotherapy and one following recurrence after 1 year of remission. Conclusion: The prognosis of rhabdomyosarcomas is linked to delays in consultation, tumour size, histological type, and therapeutic difficulties. Adequate management of this condition requires multidisciplinary consultation.http://www.sciencedirect.com/science/article/pii/S2213576623000593Case seriesChildPelvisPrognosisRhabdomyosarcoma |
| spellingShingle | Kokoé Agblévi Midékor Gonébo Moufidath Sounkéré Soro Rébécca Bonny Obro Amenan Kan Sophie Kouassi Dria Sigué Jean Jaurès Ouattara Yapi Landry Aké Nicolas Moh Ello Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series Journal of Pediatric Surgery Case Reports Case series Child Pelvis Prognosis Rhabdomyosarcoma |
| title | Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series |
| title_full | Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series |
| title_fullStr | Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series |
| title_full_unstemmed | Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series |
| title_short | Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series |
| title_sort | prognosis of childhood abdominopelvic rhabdomyosarcoma case series |
| topic | Case series Child Pelvis Prognosis Rhabdomyosarcoma |
| url | http://www.sciencedirect.com/science/article/pii/S2213576623000593 |
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