Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature

Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature

The fibrous tumors of the pleura are rare primary tumors, accounting for 5% of malignant pleural neoplasms, which generally originate from sub-mesothelial mesenchymal tissue of the visceral pleura. These tumours generally exhibit clinical benign behavior although 12% of solitary fibrous tumors can b...

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Bibliographic Details
Main Authors: Perrotta Fabio, Cerqua Francesco Saverio, Cammarata Antonino, Izzo Alessandro, Bergaminelli Carlo, Curcio Carlo, Guarino Carmine, Grella Edoardo, Forzano Imma, Cennamo Antonio, Tafuri Domenico, Rocca Aldo, Bianco Andrea, Mazzarella Gennaro
Format: Article
Language:English
Published: De Gruyter 2016-01-01
Series:Open Medicine
Subjects:
solitary fibrous tumor of the pleura (sftp)
surgical treatment
embolization
giant tumors
Online Access:https://doi.org/10.1515/med-2016-0042
Description
Summary:The fibrous tumors of the pleura are rare primary tumors, accounting for 5% of malignant pleural neoplasms, which generally originate from sub-mesothelial mesenchymal tissue of the visceral pleura. These tumours generally exhibit clinical benign behavior although 12% of solitary fibrous tumors can be malignant and have worse outcomes. These tumors are considered “giant” when the lesion > 15 cm. Surgical treatment is the best choice for both benign and malignant neoplasms. We retrospectively analyzed the main case series of giant fibrous tumors of the pleura. In addition we report our experience of a 76-year-old woman treated by pre-surgical embolization involving implantation of vascular plugs. Surgery was successfully carried out without complications; imaging and functional assessment 6 months post intervention demonstrated both the absence of recurrence and improvement of lung function parameters.
ISSN:2391-5463

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