PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
PEG-embedded potassium tribromide ([K+PEG]Br3−) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K+PEG]Br3− was readily...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2011-09-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.7.157 |
| _version_ | 1818445478312804352 |
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| author | Sanny Verma Suman L. Jain Bir Sain |
| author_facet | Sanny Verma Suman L. Jain Bir Sain |
| author_sort | Sanny Verma |
| collection | DOAJ |
| description | PEG-embedded potassium tribromide ([K+PEG]Br3−) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K+PEG]Br3− was readily regenerated from the reaction mixture by treating the residue containing [K+PEG]Br− with molecular bromine. |
| first_indexed | 2024-12-14T19:32:28Z |
| format | Article |
| id | doaj.art-d302718ce7ba4a49ab4c408a068b3d64 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-14T19:32:28Z |
| publishDate | 2011-09-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-d302718ce7ba4a49ab4c408a068b3d642022-12-21T22:50:03ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972011-09-01711334134110.3762/bjoc.7.1571860-5397-7-157PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidinesSanny Verma0Suman L. Jain1Bir Sain2Chemical Sciences Division, Indian Institute of Petroleum (Council of Scientific and Industrial Research), Dehradun-248005, IndiaChemical Sciences Division, Indian Institute of Petroleum (Council of Scientific and Industrial Research), Dehradun-248005, IndiaChemical Sciences Division, Indian Institute of Petroleum (Council of Scientific and Industrial Research), Dehradun-248005, IndiaPEG-embedded potassium tribromide ([K+PEG]Br3−) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K+PEG]Br3− was readily regenerated from the reaction mixture by treating the residue containing [K+PEG]Br− with molecular bromine.https://doi.org/10.3762/bjoc.7.157heterocyclesmetal free synthesismulticomponent couplingpiperidinerecyclable catalyst |
| spellingShingle | Sanny Verma Suman L. Jain Bir Sain PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines Beilstein Journal of Organic Chemistry heterocycles metal free synthesis multicomponent coupling piperidine recyclable catalyst |
| title | PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines |
| title_full | PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines |
| title_fullStr | PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines |
| title_full_unstemmed | PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines |
| title_short | PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines |
| title_sort | peg embedded kbr3 a recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines |
| topic | heterocycles metal free synthesis multicomponent coupling piperidine recyclable catalyst |
| url | https://doi.org/10.3762/bjoc.7.157 |
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