Lysophospholipids and Their G-Coupled Protein Signaling in Alzheimer’s Disease: From Physiological Performance to Pathological Impairment

Lysophospholipids and Their G-Coupled Protein Signaling in Alzheimer’s Disease: From Physiological Performance to Pathological Impairment

Lysophospholipids (LPLs) are bioactive signaling lipids that are generated from phospholipase-mediated hydrolyzation of membrane phospholipids (PLs) and sphingolipids (SLs). Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are two of the best-characterized LPLs which mediate a variety o...

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Bibliographic Details
Main Authors:	Yining Hao, Min Guo, Yiwei Feng, Qiang Dong, Mei Cui
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-04-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	lysophospholipids lysophosphatidic acid (LPA) sphingosine-1-phosphate (S1P) G-protein coupled receptor (GPCR) Alzheimer’s disease (AD)
Online Access:	https://www.frontiersin.org/article/10.3389/fnmol.2020.00058/full

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