Tonsillar Microbiome‐Derived Lantibiotics Induce Structural Changes of IL‐6 and IL‐21 Receptors and Modulate Host Immunity

Tonsillar Microbiome‐Derived Lantibiotics Induce Structural Changes of IL‐6 and IL‐21 Receptors and Modulate Host Immunity

Abstract Emerging evidence emphasizes the functional impacts of host microbiome on the etiopathogenesis of autoimmune diseases, including rheumatoid arthritis (RA). However, there are limited mechanistic insights into the contribution of microbial biomolecules especially microbial peptides toward mo...

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Main Authors: Jing Li, Jiayang Jin, Shenghui Li, Yan Zhong, Yuebo Jin, Xuan Zhang, Binbin Xia, Yinhua Zhu, Ruochun Guo, Xiaolin Sun, Jianping Guo, Fanlei Hu, Wenjing Xiao, Fei Huang, Hua Ye, Ru Li, Yunshan Zhou, Xiaohong Xiang, Haihong Yao, Qiulong Yan, Li Su, Lijun Wu, Tuoping Luo, Yudong Liu, Xiaohuan Guo, Junjie Qin, Hai Qi, Jing He, Jun Wang, Zhanguo Li
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Advanced Science
Subjects:
IL‐6 and IL‐21 receptor
lantibiotics
tonsillar microbiome
rheumatoid arthritis
salivaricins
Online Access:https://doi.org/10.1002/advs.202202706

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