Changes in expression of the long noncoding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells

Changes in expression of the long noncoding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells

CGG repeat expansions in the Fragile X mental retardation 1 (FMR1) gene are responsible for a family of associated disorders characterized by either intellectual disability and autism (Fragile X Syndrome, FXS), or adult-onset neurodegeneration (Fragile X-associated Tremor/Ataxia Syndrome, FXTAS). Ho...

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Bibliographic Details
Main Authors: Veronica Julia Peschansky, Chiara ePastori, Zane eZeier, Dario eMotti, Katya eWentzel, Dmitry eVelmeshev, Marco eMagistri, John L Bixby, Vance P Lemmon, José P Silva, Claes eWahlestedt
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Genetics
Subjects:
Fragile X Syndrome
Intellectual Disability
epigenetics
differentiation
Chromatin remodeling
lncRNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00263/full

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