Polyethylene Glycol Ointment Alleviates Psoriasis-Like Inflammation Through Down-Regulating the Function of Th17 Cells and MDSCs

Polyethylene Glycol Ointment Alleviates Psoriasis-Like Inflammation Through Down-Regulating the Function of Th17 Cells and MDSCs

Objective: To explore the possible mechanism of improving the imiquimod (IMQ)-induced psoriasis-like inflammation by using polyethylene glycol (PEG) ointment.Methods: We evaluated the appearance of psoriasis lesions by Psoriasis Area and Severity Index (PASI), observed the epidermal proliferation by...

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Bibliographic Details
Main Authors: Yan Lu, Yi Xiao, Ming-Zhu Yin, Xing-Chen Zhou, Li-Sha Wu, Wang-Qing Chen, Yan Luo, Ye-Hong Kuang, Wu Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Medicine
Subjects:
psoriasis
IMQ
PEG
MDSCs
Th17
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.560579/full

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