Anti-inflammatory and regenerative effects of MKARE® Eggshell Membrane: An in vitro osteoarthritis model and placebo-controlled clinical study

MKARE®, a 100% natural ingredient derived from fresh eggshell membrane (ESM), has a rich composition in bioactive compounds like collagen, hyaluronic acid, and elastin. These components are beneficial for managing osteoarthritis (OA) due to their anti-inflammatory and regenerative properties. Highli...

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Bibliographic Details
Main Authors: Alejandro Casado-Santos, Manuel A. La Nuez-García, Patricia Álvarez-Rodríguez, Elsa González-Cubero, Yaiza González-Rodríguez, Maria Luisa González-Fernández, Vega Villar-Suárez
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Functional Foods
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Online Access:http://www.sciencedirect.com/science/article/pii/S175646462400121X
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Summary:MKARE®, a 100% natural ingredient derived from fresh eggshell membrane (ESM), has a rich composition in bioactive compounds like collagen, hyaluronic acid, and elastin. These components are beneficial for managing osteoarthritis (OA) due to their anti-inflammatory and regenerative properties. Highlighting the significance of freshness, our research has shown that the effectiveness of MKARE® is higher than that of other commercial products based on ESM that have been stored for several days at room temperature, losing their bioactive compounds. This study explores the MKARE® anti-inflammatory capacity through an in vitro and clinical analyses, demonstrating its ability to alleviate OA symptoms and improve joint health. This underscores the crucial role of freshness in optimizing the therapeutic benefits.
ISSN:1756-4646