Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary
Background: The Infants and Toddlers Dermatology Quality of Life (InToDermQoL) questionnaire is the first dermatology-specific proxy health related QoL instrument for children from birth to 4 years. Score meaning bands and the sensitivity to successful therapeutic intervention are important to inter...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | JAAD International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666328722001572 |
| _version_ | 1828035832600068096 |
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| author | Pavel V. Chernyshov, MD, PhD Servando E. Marron, MD Michael J. Boffa, MD, MSc Nives Pustišek, MD, PhD Liana Manolache, MD, PhD Talia Kakourou, MD, PhD Monique Cachia, MD Tetiana Svyatenko, MD, PhD, DrSc Dimitra Koumaki, MD, PhD Andrii V. Chernyshov, MD, PhD Lucia Tomas-Aragones, PhD |
| author_facet | Pavel V. Chernyshov, MD, PhD Servando E. Marron, MD Michael J. Boffa, MD, MSc Nives Pustišek, MD, PhD Liana Manolache, MD, PhD Talia Kakourou, MD, PhD Monique Cachia, MD Tetiana Svyatenko, MD, PhD, DrSc Dimitra Koumaki, MD, PhD Andrii V. Chernyshov, MD, PhD Lucia Tomas-Aragones, PhD |
| author_sort | Pavel V. Chernyshov, MD, PhD |
| collection | DOAJ |
| description | Background: The Infants and Toddlers Dermatology Quality of Life (InToDermQoL) questionnaire is the first dermatology-specific proxy health related QoL instrument for children from birth to 4 years. Score meaning bands and the sensitivity to successful therapeutic intervention are important to interpret the clinical meaning of an instrument. Objective: The aim of the present study was to check the sensitivity to successful therapeutic intervention and establish score bands of the InToDermQoL questionnaire. Methods: Parents or grandparents of 424 children with skin diseases from Spain, Malta, Croatia, Romania, Greece, and Ukraine filled in national language versions of the InToDermQoL questionnaire. Disease severity of children with atopic dermatitis was assessed by SCORAD (Scoring atopic dermatitis). Cohen’s d was used to assess the responsiveness of the instrument. Results: The mean total InToDermQoL scores significantly decreased after treatment. Severity grading of the SCORAD scores gave stratification of the InToDermQoL severity grades based on 95% confidence intervals. Scores below a calculated minimal important difference of 2 corresponded to no effect on patient’s health related QoL. Limitations: Score banding may be slightly different across patient population and study context. Conclusion: All 3 age-specific versions of the InToDermQoL questionnaire showed sensitivity to treatment. Score bands for the InToDermQoL questionnaire have been established. |
| first_indexed | 2024-04-10T15:52:11Z |
| format | Article |
| id | doaj.art-d30a42302d274985a3d1600e25c23722 |
| institution | Directory Open Access Journal |
| issn | 2666-3287 |
| language | English |
| last_indexed | 2024-04-10T15:52:11Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JAAD International |
| spelling | doaj.art-d30a42302d274985a3d1600e25c237222023-02-11T04:16:27ZengElsevierJAAD International2666-32872023-03-01106167Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule SummaryPavel V. Chernyshov, MD, PhD0Servando E. Marron, MD1Michael J. Boffa, MD, MSc2Nives Pustišek, MD, PhD3Liana Manolache, MD, PhD4Talia Kakourou, MD, PhD5Monique Cachia, MD6Tetiana Svyatenko, MD, PhD, DrSc7Dimitra Koumaki, MD, PhD8Andrii V. Chernyshov, MD, PhD9Lucia Tomas-Aragones, PhD10Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine; Correspondence to: Pavel V. Chernyshov, MD, PhD, Department of Dermatology and Venereology, National Medical University, 13 Bulvar Shevchenko, Kiev, 01601, Ukraine.Department of Dermatology, University Hospital Miguel Servet, Aragon Psychodermatology Research Group (GAI+PD), Zaragoza, SpainDepartment of Dermatology, Mater Dei Hospital, Msida, MaltaChildren's Hospital Zagreb, Medical School, University of Zagreb, Zagreb, CroatiaDermatology, Dali Medical, Bucharest, RomaniaFirst Pediatric Department of Athens University, Aghia Sophia Children’s Hospital, Athens, GreeceDepartment of Dermatology, Mater Dei Hospital, Msida, MaltaDepartment of Skin and Venereal Diseases, Dnipro State Medical University, Dnipro, UkraineDepartment of Dermatology and Venereology, University Hospital of Heraklion, Heraklion, Crete, GreeceDepartment of Cellular Radiobiology, State Institution “National Research Center for Radiation Medicine of National Academy of Medical Sciences of Ukraine”, Kiev, UkraineDepartment of Psychology, University of Zaragoza, Zaragoza, SpainBackground: The Infants and Toddlers Dermatology Quality of Life (InToDermQoL) questionnaire is the first dermatology-specific proxy health related QoL instrument for children from birth to 4 years. Score meaning bands and the sensitivity to successful therapeutic intervention are important to interpret the clinical meaning of an instrument. Objective: The aim of the present study was to check the sensitivity to successful therapeutic intervention and establish score bands of the InToDermQoL questionnaire. Methods: Parents or grandparents of 424 children with skin diseases from Spain, Malta, Croatia, Romania, Greece, and Ukraine filled in national language versions of the InToDermQoL questionnaire. Disease severity of children with atopic dermatitis was assessed by SCORAD (Scoring atopic dermatitis). Cohen’s d was used to assess the responsiveness of the instrument. Results: The mean total InToDermQoL scores significantly decreased after treatment. Severity grading of the SCORAD scores gave stratification of the InToDermQoL severity grades based on 95% confidence intervals. Scores below a calculated minimal important difference of 2 corresponded to no effect on patient’s health related QoL. Limitations: Score banding may be slightly different across patient population and study context. Conclusion: All 3 age-specific versions of the InToDermQoL questionnaire showed sensitivity to treatment. Score bands for the InToDermQoL questionnaire have been established.http://www.sciencedirect.com/science/article/pii/S2666328722001572patient-reported outcome measurespediatric dermatologyquality of lifetreatmentseverity banding |
| spellingShingle | Pavel V. Chernyshov, MD, PhD Servando E. Marron, MD Michael J. Boffa, MD, MSc Nives Pustišek, MD, PhD Liana Manolache, MD, PhD Talia Kakourou, MD, PhD Monique Cachia, MD Tetiana Svyatenko, MD, PhD, DrSc Dimitra Koumaki, MD, PhD Andrii V. Chernyshov, MD, PhD Lucia Tomas-Aragones, PhD Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary JAAD International patient-reported outcome measures pediatric dermatology quality of life treatment severity banding |
| title | Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary |
| title_full | Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary |
| title_fullStr | Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary |
| title_full_unstemmed | Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary |
| title_short | Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary |
| title_sort | sensitivity to treatment and score bands of the infants and toddlers dermatology quality of life questionnairecapsule summary |
| topic | patient-reported outcome measures pediatric dermatology quality of life treatment severity banding |
| url | http://www.sciencedirect.com/science/article/pii/S2666328722001572 |
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