Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains.

Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains.

The implication of soluble Abeta in the Alzheimer's disease (AD) pathology is currently accepted. In fact, the content of soluble extracellular Abeta species, such as monomeric and/or oligomeric Abeta, seems to correlate with the clinico-pathological dysfunction observed in AD patients. However...

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Bibliographic Details
Main Authors:	Sebastian Jimenez, Victoria Navarro, Javier Moyano, María Sanchez-Mico, Manuel Torres, Jose Carlos Davila, Marisa Vizuete, Antonia Gutierrez, Javier Vitorica
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4259387?pdf=render

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