SARS-CoV-2 envelope protein triggers depression-like behaviors and dysosmia via TLR2-mediated neuroinflammation in mice
Abstract Background Depression and dysosmia have been regarded as primary neurological symptoms in COVID-19 patients, the mechanism of which remains unclear. Current studies have demonstrated that the SARS-CoV-2 envelope (E) protein is a pro-inflammatory factor sensed by Toll-like receptor 2 (TLR2),...
Main Authors: | Wenliang Su, Jiahang Ju, Minghui Gu, Xinrui Wang, Shaozhuang Liu, Jiawen Yu, Dongliang Mu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-023-02786-x |
Similar Items
-
Rational approach to the treatment of acute rhinosinusitis in comorbides with dysosmia
by: S. V. Morozova, et al.
Published: (2020-05-01) -
Reduced olfactory performance is associated with changed microbial diversity, oralization, and accumulation of dead biomaterial in the nasal olfactory area
by: Christina Kumpitsch, et al.
Published: (2024-02-01) -
Symptomatic Characteristics of Hypozincemia Detected in Long COVID Patients
by: Yui Matsuda, et al.
Published: (2023-03-01) -
Dysgeusia in Patients with Breast Cancer Treated with Chemotherapy—A Narrative Review
by: Marianna Pellegrini, et al.
Published: (2023-01-01) -
Olfactory Dysfunction in Patients with Coronavirus Disease 2019: A Narrative Review
by: Mehdi Askari
Published: (2023-04-01)