Using High Resolution Melting Method for Detecting Nucleotide Polymorphisms of STK11 Gene Germline in Patients with Digestive System Cancers

Using High Resolution Melting Method for Detecting Nucleotide Polymorphisms of STK11 Gene Germline in Patients with Digestive System Cancers

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Background and Objective: High resolution melting (HRM) analysis is a technique to measure decrease of fluoresce, caused by discharge of the dye, throughout DNA thermal melting gradient process. STK11 gene encodes one of cellular serine-threonine kinase proteins that regulates cellular polarity. It...

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Bibliographic Details
Main Authors: Seyed Jamal Hosseini, Ali Nazemi, Mehrdad Hashemi, Mirsaed Miri Nargesi, Sharashout Sharirfi, Farhad Shaveisi Zadeh, Ali Asghar Karaminia, Abolfazl Movafagh
Format: Article
Language:English
Published: West Asia Organization for Cancer Prevention 2016-06-01
Series:Asian Pacific Journal of Cancer Biology
Subjects:
stk11 gene, mutation of germline, high resolution melting
Online Access:http://www.waocp.com/journal/index.php/apjcb/article/view/197

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