COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine
COPD patients with asthma features usually benefit from inhaled corticosteroids (ICS)-containing regimens, but their burden and diagnostic criteria remain to be established. The aims of this study were to estimate the proportion of patients with asthma features among patients with physician-diagnose...
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| Format: | Article |
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MDPI AG
2023-05-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/6/901 |
| _version_ | 1797593950248239104 |
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| author | Nguyen Van Tho Thu Phuong Phan Anh Tuan Dinh-Xuan Quy Chau Ngo Le Thi Tuyet Lan |
| author_facet | Nguyen Van Tho Thu Phuong Phan Anh Tuan Dinh-Xuan Quy Chau Ngo Le Thi Tuyet Lan |
| author_sort | Nguyen Van Tho |
| collection | DOAJ |
| description | COPD patients with asthma features usually benefit from inhaled corticosteroids (ICS)-containing regimens, but their burden and diagnostic criteria remain to be established. The aims of this study were to estimate the proportion of patients with asthma features among patients with physician-diagnosed COPD and to investigate differences in clinical characteristics and current medications between COPD patients with asthma features and patients with COPD alone. A cross-sectional study was conducted at two respiratory out-patient clinics at the University Medical Center in Ho Chi Minh City and Bach Mai Hospital in Ha Noi, Vietnam. COPD patients with asthma features were identified by attending physicians following the approach recommended by the GINA/GOLD joint committee. Of the 332 patients screened, 300 were enrolled in the study. The proportion of COPD patients with asthma features was 27.3% (95% confidence interval (95% CI) 22.6–32.6%). COPD patients with asthma features were younger, with higher FEV<sub>1</sub> values, a greater proportion of positive bronchodilator reversibility tests, higher blood eosinophil count, and were more often treated with ICS/LABA (ICS/long-acting bronchodilator beta-2 agonist) than patients with COPD alone. The prevalence of COPD patients with asthma features is particularly high in Vietnam thus requiring appropriate action plans in clinical practice. |
| first_indexed | 2024-03-11T02:16:48Z |
| format | Article |
| id | doaj.art-d30ed982c6b34e47b3cf5a2c770d56b1 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-11T02:16:48Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-d30ed982c6b34e47b3cf5a2c770d56b12023-11-18T11:10:19ZengMDPI AGJournal of Personalized Medicine2075-44262023-05-0113690110.3390/jpm13060901COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized MedicineNguyen Van Tho0Thu Phuong Phan1Anh Tuan Dinh-Xuan2Quy Chau Ngo3Le Thi Tuyet Lan4Department of Tuberculosis and Lung Diseases, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, VietnamDepartment of Internal Medicine, Ha Noi Medical University, Ha Noi City, VietnamAP-HP, Hôpital Cochin, Service de Physiologie-Explorations Fonctionnelles, Paris, FranceDepartment of Internal Medicine, Ha Noi Medical University, Ha Noi City, VietnamDepartment of Pulmonary Functional Exploration, University Medical Center at Ho Chi Minh City, Ho Chi Minh City, VietnamCOPD patients with asthma features usually benefit from inhaled corticosteroids (ICS)-containing regimens, but their burden and diagnostic criteria remain to be established. The aims of this study were to estimate the proportion of patients with asthma features among patients with physician-diagnosed COPD and to investigate differences in clinical characteristics and current medications between COPD patients with asthma features and patients with COPD alone. A cross-sectional study was conducted at two respiratory out-patient clinics at the University Medical Center in Ho Chi Minh City and Bach Mai Hospital in Ha Noi, Vietnam. COPD patients with asthma features were identified by attending physicians following the approach recommended by the GINA/GOLD joint committee. Of the 332 patients screened, 300 were enrolled in the study. The proportion of COPD patients with asthma features was 27.3% (95% confidence interval (95% CI) 22.6–32.6%). COPD patients with asthma features were younger, with higher FEV<sub>1</sub> values, a greater proportion of positive bronchodilator reversibility tests, higher blood eosinophil count, and were more often treated with ICS/LABA (ICS/long-acting bronchodilator beta-2 agonist) than patients with COPD alone. The prevalence of COPD patients with asthma features is particularly high in Vietnam thus requiring appropriate action plans in clinical practice.https://www.mdpi.com/2075-4426/13/6/901asthmachronic obstructive pulmonary diseaseCOPDoverlap |
| spellingShingle | Nguyen Van Tho Thu Phuong Phan Anh Tuan Dinh-Xuan Quy Chau Ngo Le Thi Tuyet Lan COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine Journal of Personalized Medicine asthma chronic obstructive pulmonary disease COPD overlap |
| title | COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine |
| title_full | COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine |
| title_fullStr | COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine |
| title_full_unstemmed | COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine |
| title_short | COPD Patients with Asthma Features in Vietnam: Prevalence and Suitability for Personalized Medicine |
| title_sort | copd patients with asthma features in vietnam prevalence and suitability for personalized medicine |
| topic | asthma chronic obstructive pulmonary disease COPD overlap |
| url | https://www.mdpi.com/2075-4426/13/6/901 |
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