A scoping review of patient selection methods for proton therapy
Abstract The aim was to explore various national and international clinical decision‐making tools and dose comparison methods used for selecting cancer patients for proton versus X‐ray radiation therapy. To address this aim, a literature search using defined scoping review methods was performed in M...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-03-01
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| Series: | Journal of Medical Radiation Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jmrs.540 |
| _version_ | 1819349413049401344 |
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| author | Nicole Zientara Eileen Giles Hien Le Michala Short |
| author_facet | Nicole Zientara Eileen Giles Hien Le Michala Short |
| author_sort | Nicole Zientara |
| collection | DOAJ |
| description | Abstract The aim was to explore various national and international clinical decision‐making tools and dose comparison methods used for selecting cancer patients for proton versus X‐ray radiation therapy. To address this aim, a literature search using defined scoping review methods was performed in Medline and Embase databases as well as grey literature. Articles published between 1 January 2015 and 4 August 2020 and those that clearly stated methods of proton versus X‐ray therapy patient selection and those published in English were eligible for inclusion. In total, 321 studies were identified of which 49 articles met the study’s inclusion criteria representing 13 countries. Six different clinical decision‐making tools and 14 dose comparison methods were identified, demonstrating variability within countries and internationally. Proton therapy was indicated for all paediatric patients except those with lymphoma and re‐irradiation where individualised model‐based selection was required. The most commonly reported patient selection tools included the Normal Tissue Complication Probability model, followed by cost‐effectiveness modelling and dosimetry comparison. Model‐based selection methods were most commonly applied for head and neck clinical indications in adult cohorts (48% of studies). While no ‘Gold Standard’ currently exists for proton therapy patient selection with variations evidenced globally, some of the patient selection methods identified in this review can be used to inform future practice in Australia. As literature was not identified from all countries where proton therapy centres are available, further research is needed to evaluate patient selection methods in these jurisdictions for a comprehensive overview. |
| first_indexed | 2024-12-24T19:00:07Z |
| format | Article |
| id | doaj.art-d311374acc644bfeb1de49198d38d426 |
| institution | Directory Open Access Journal |
| issn | 2051-3895 2051-3909 |
| language | English |
| last_indexed | 2024-12-24T19:00:07Z |
| publishDate | 2022-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Medical Radiation Sciences |
| spelling | doaj.art-d311374acc644bfeb1de49198d38d4262022-12-21T16:43:14ZengWileyJournal of Medical Radiation Sciences2051-38952051-39092022-03-0169110812110.1002/jmrs.540A scoping review of patient selection methods for proton therapyNicole Zientara0Eileen Giles1Hien Le2Michala Short3UniSA Cancer Research Institute UniSA Allied Health and Human Performance University of South Australia Adelaide South Australia AustraliaUniSA Cancer Research Institute UniSA Allied Health and Human Performance University of South Australia Adelaide South Australia AustraliaUniSA Cancer Research Institute UniSA Allied Health and Human Performance University of South Australia Adelaide South Australia AustraliaUniSA Cancer Research Institute UniSA Allied Health and Human Performance University of South Australia Adelaide South Australia AustraliaAbstract The aim was to explore various national and international clinical decision‐making tools and dose comparison methods used for selecting cancer patients for proton versus X‐ray radiation therapy. To address this aim, a literature search using defined scoping review methods was performed in Medline and Embase databases as well as grey literature. Articles published between 1 January 2015 and 4 August 2020 and those that clearly stated methods of proton versus X‐ray therapy patient selection and those published in English were eligible for inclusion. In total, 321 studies were identified of which 49 articles met the study’s inclusion criteria representing 13 countries. Six different clinical decision‐making tools and 14 dose comparison methods were identified, demonstrating variability within countries and internationally. Proton therapy was indicated for all paediatric patients except those with lymphoma and re‐irradiation where individualised model‐based selection was required. The most commonly reported patient selection tools included the Normal Tissue Complication Probability model, followed by cost‐effectiveness modelling and dosimetry comparison. Model‐based selection methods were most commonly applied for head and neck clinical indications in adult cohorts (48% of studies). While no ‘Gold Standard’ currently exists for proton therapy patient selection with variations evidenced globally, some of the patient selection methods identified in this review can be used to inform future practice in Australia. As literature was not identified from all countries where proton therapy centres are available, further research is needed to evaluate patient selection methods in these jurisdictions for a comprehensive overview.https://doi.org/10.1002/jmrs.540Clinical decision‐makingdecision support techniquespatient selectionproton therapyradiotherapy |
| spellingShingle | Nicole Zientara Eileen Giles Hien Le Michala Short A scoping review of patient selection methods for proton therapy Journal of Medical Radiation Sciences Clinical decision‐making decision support techniques patient selection proton therapy radiotherapy |
| title | A scoping review of patient selection methods for proton therapy |
| title_full | A scoping review of patient selection methods for proton therapy |
| title_fullStr | A scoping review of patient selection methods for proton therapy |
| title_full_unstemmed | A scoping review of patient selection methods for proton therapy |
| title_short | A scoping review of patient selection methods for proton therapy |
| title_sort | scoping review of patient selection methods for proton therapy |
| topic | Clinical decision‐making decision support techniques patient selection proton therapy radiotherapy |
| url | https://doi.org/10.1002/jmrs.540 |
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