The Shank3 interaction partner ProSAPiP1 regulates postsynaptic SPAR levels and the maturation of dendritic spines in hippocampal neurons

The Shank3 interaction partner ProSAPiP1 regulates postsynaptic SPAR levels and the maturation of dendritic spines in hippocampal neurons

The postsynaptic density or PSD is a submembranous compartment containing a wide array of proteins that contribute to both morphology and function of excitatory glutamatergic synapses. In this study, we have analyzed functional aspects of the Fezzin ProSAPiP1, an interaction partner of the well-know...

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Bibliographic Details
Main Authors: Dominik eReim, Tobias eWeis, Sonja eHalbedl, Andreas eGrabrucker, Michael J Schmeisser, Tobias Maria Boeckers
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
synapse
Shank3
spar
LZTS1
LAPSER1
LZTS2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00013/full

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