Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats

Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats

The aim of the present research was to describe the consequences of hyperlipidemia (HL) on the pharmacokinetics of glibenclamide (Gb) in poloxamer 407-induced hyperlipidemic rats. Rats were given intraperitoneal dose of poloxamer 407 to cause hyperlipidemia. A single oral dose of Gb (10 mg/Kg) was g...

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Bibliographic Details
Main Authors:	Yousef A. Bin Jardan, Abdul Ahad, Mohammad Raish, Ajaz Ahmad, Mohd Aftab Alam, Abdullah M. Al-Mohizea, Fahad I. Al-Jenoobi
Format:	Article
Language:	English
Published:	Elsevier 2021-07-01
Series:	Saudi Pharmaceutical Journal
Subjects:	Diabetes Glyburide Hyperlipidemia Lipoproteins Rats
Online Access:	http://www.sciencedirect.com/science/article/pii/S1319016421000992

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