Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022
Pharmacological management of airway obstructive diseases is a fast-evolving field. Several advances in unravelling disease mechanisms as well as intracellular and molecular pathways of drug action have been accomplished. While the clinical translation and implementation of in vitro results to the b...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2023-06-01
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| Series: | Breathe |
| Online Access: | http://breathe.ersjournals.com/content/19/2/220267.full |
| _version_ | 1797731322828947456 |
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| author | Daiana Stolz Maria Gabriella Matera Paola Rogliani Maarten van den Berge Eleni Papakonstantinou Reinoud Gosens Dave Singh Nicola Hanania Mario Cazzola Anke-Hilse Maitland-van der Zee Laura Fregonese Alexander G. Mathioudakis Jørgen Vestbo Maia Rukhadze Clive P. Page |
| author_facet | Daiana Stolz Maria Gabriella Matera Paola Rogliani Maarten van den Berge Eleni Papakonstantinou Reinoud Gosens Dave Singh Nicola Hanania Mario Cazzola Anke-Hilse Maitland-van der Zee Laura Fregonese Alexander G. Mathioudakis Jørgen Vestbo Maia Rukhadze Clive P. Page |
| author_sort | Daiana Stolz |
| collection | DOAJ |
| description | Pharmacological management of airway obstructive diseases is a fast-evolving field. Several advances in unravelling disease mechanisms as well as intracellular and molecular pathways of drug action have been accomplished. While the clinical translation and implementation of in vitro results to the bedside remains challenging, advances in comprehending the mechanisms of respiratory medication are expected to assist clinicians and scientists in identifying meaningful read-outs and designing clinical studies. This European Respiratory Society Research Seminar, held in Naples, Italy, 5–6 May 2022, focused on current and future developments of the drugs used to treat asthma and COPD; on mechanisms of drug action, steroid resistance, comorbidities and drug interactions; on prognostic and therapeutic biomarkers; on developing novel drug targets based on tissue remodelling and regeneration; and on pharmacogenomics and emerging biosimilars. Related European Medicines Agency regulations are also discussed, as well as the seminar's position on the above aspects. |
| first_indexed | 2024-03-12T11:57:05Z |
| format | Article |
| id | doaj.art-d318550bc22949b8b4e3a6be9a3c1560 |
| institution | Directory Open Access Journal |
| issn | 1810-6838 2073-4735 |
| language | English |
| last_indexed | 2024-03-12T11:57:05Z |
| publishDate | 2023-06-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | Breathe |
| spelling | doaj.art-d318550bc22949b8b4e3a6be9a3c15602023-08-30T15:30:24ZengEuropean Respiratory SocietyBreathe1810-68382073-47352023-06-0119210.1183/20734735.0267-20220267-2022Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022Daiana Stolz0Maria Gabriella Matera1Paola Rogliani2Maarten van den Berge3Eleni Papakonstantinou4Reinoud Gosens5Dave Singh6Nicola Hanania7Mario Cazzola8Anke-Hilse Maitland-van der Zee9Laura Fregonese10Alexander G. Mathioudakis11Jørgen Vestbo12Maia Rukhadze13Clive P. Page14 Clinic of Pulmonary Medicine, Department of Internal Medicine, Medical Center University of Freiburg, Freiburg, Germany Unit of Pharmacology, Department of Experimental Medicine, School of Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy Unit of Respiratory Medicine, Department Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy Groningen Research Institute for Asthma and COPD, and Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Clinic of Pulmonary Medicine, Department of Internal Medicine, Medical Center University of Freiburg, Freiburg, Germany Groningen Research Institute for Asthma and COPD, and Department of Molecular Pharmacology, Groningen Research Institute of Pharmacy, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Medicines Evaluation Unit, Manchester University NHS Foundation Trust, University of Manchester, Manchester, UK Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX, USA Unit of Respiratory Medicine, Department Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy Department of Pulmonary Medicine, University of Amsterdam, Amsterdam University Medical Centres, Amsterdam, The Netherlands European Medicines Agency, London, UK Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester and Manchester University NHS Foundation Trust, Manchester, UK Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester and Manchester University NHS Foundation Trust, Manchester, UK Center of Allergy and Immunology, Teaching University Geomedi LLC, Tbilisi, Georgia Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK Pharmacological management of airway obstructive diseases is a fast-evolving field. Several advances in unravelling disease mechanisms as well as intracellular and molecular pathways of drug action have been accomplished. While the clinical translation and implementation of in vitro results to the bedside remains challenging, advances in comprehending the mechanisms of respiratory medication are expected to assist clinicians and scientists in identifying meaningful read-outs and designing clinical studies. This European Respiratory Society Research Seminar, held in Naples, Italy, 5–6 May 2022, focused on current and future developments of the drugs used to treat asthma and COPD; on mechanisms of drug action, steroid resistance, comorbidities and drug interactions; on prognostic and therapeutic biomarkers; on developing novel drug targets based on tissue remodelling and regeneration; and on pharmacogenomics and emerging biosimilars. Related European Medicines Agency regulations are also discussed, as well as the seminar's position on the above aspects.http://breathe.ersjournals.com/content/19/2/220267.full |
| spellingShingle | Daiana Stolz Maria Gabriella Matera Paola Rogliani Maarten van den Berge Eleni Papakonstantinou Reinoud Gosens Dave Singh Nicola Hanania Mario Cazzola Anke-Hilse Maitland-van der Zee Laura Fregonese Alexander G. Mathioudakis Jørgen Vestbo Maia Rukhadze Clive P. Page Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022 Breathe |
| title | Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022 |
| title_full | Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022 |
| title_fullStr | Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022 |
| title_full_unstemmed | Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022 |
| title_short | Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022 |
| title_sort | current and future developments in the pharmacology of asthma and copd ers seminar naples 2022 |
| url | http://breathe.ersjournals.com/content/19/2/220267.full |
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