Genome-wide methylation profiling identify hypermethylated HOXL subclass genes as potential markers for esophageal squamous cell carcinoma detection

Genome-wide methylation profiling identify hypermethylated HOXL subclass genes as potential markers for esophageal squamous cell carcinoma detection

Abstract Background Numerous studies have revealed aberrant DNA methylation in esophageal squamous cell carcinoma (ESCC). However, they often focused on the partial genome, which resulted in an inadequate understanding of the shaped methylation features and the lack of available methylation markers...

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Bibliographic Details
Main Authors: Qiuning Yu, Namei Xia, Yanteng Zhao, Huifang Jin, Renyin Chen, Fanglei Ye, Liyinghui Chen, Ying Xie, Kangkang Wan, Jun Zhou, Dihan Zhou, Xianping Lv
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medical Genomics
Subjects:
DNA methylation
Esophageal squamous cell carcinoma
HOXL subclass
Early detection markers
Online Access:https://doi.org/10.1186/s12920-022-01401-x

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