Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage
Increased oxidative stress contributes to cataract formation during aging. Anterior epithelial cells are a frontline antioxidant defense system with powerful capacities to maintain redox homeostasis and lens transparency. In this study, we report a new molecular mechanism of connexin (Cx) hemichanne...
Main Authors: | Yumeng Quan, Yu Du, Changrui Wu, Sumin Gu, Jean X. Jiang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231721002615 |
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