Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study.
The benefits and efficacy of control programs for herds infected with Mycobacterium avium subsp. paratuberculosis (MAP) have been investigated under various contexts. However, most previous research investigated paratuberculosis control programs in isolation, without modeling the potential associati...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2019-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0217888 |
| _version_ | 1828957428327120896 |
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| author | Leslie J Verteramo Chiu Loren W Tauer Yrjo T Gröhn Rebecca L Smith |
| author_facet | Leslie J Verteramo Chiu Loren W Tauer Yrjo T Gröhn Rebecca L Smith |
| author_sort | Leslie J Verteramo Chiu |
| collection | DOAJ |
| description | The benefits and efficacy of control programs for herds infected with Mycobacterium avium subsp. paratuberculosis (MAP) have been investigated under various contexts. However, most previous research investigated paratuberculosis control programs in isolation, without modeling the potential association with other dairy diseases. This paper evaluated the benefits of MAP control programs when the herd is also affected by mastitis, a common disease causing the largest losses in dairy production. The effect of typically suggested MAP controls were estimated under the assumption that MAP infection increased the rate of clinical mastitis. We evaluated one hundred twenty three control strategies comprising various combinations of testing, culling, and hygiene, and found that the association of paratuberculosis with mastitis alters the ranking of specific MAP control programs, but only slightly alters the cost-benefit difference of particular MAP control components, as measured by the distribution of net present value of a representative U.S. dairy operation. In particular, although testing and culling for MAP resulted in a reduction in MAP incidence, that control led to lower net present value (NPV) per cow. When testing was used, ELISA was more economically beneficial than alternative testing regimes, especially if mastitis was explicitly modeled as more likely in MAP-infected animals, but ELISA testing was only significantly associated with higher NPV if mastitis was not included in the model at all. Additional hygiene was associated with a lower NPV per cow, although it lowered MAP prevalence. Overall, the addition of an increased risk of mastitis in MAP-infected animals did not change model recommendations as much as failing to consider. |
| first_indexed | 2024-12-14T08:28:19Z |
| format | Article |
| id | doaj.art-d32abdcc2b32412c92e7594d02b82b27 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T08:28:19Z |
| publishDate | 2019-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d32abdcc2b32412c92e7594d02b82b272022-12-21T23:09:34ZengPublic Library of Science (PLoS)PLoS ONE1932-62032019-01-01149e021788810.1371/journal.pone.0217888Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study.Leslie J Verteramo ChiuLoren W TauerYrjo T GröhnRebecca L SmithThe benefits and efficacy of control programs for herds infected with Mycobacterium avium subsp. paratuberculosis (MAP) have been investigated under various contexts. However, most previous research investigated paratuberculosis control programs in isolation, without modeling the potential association with other dairy diseases. This paper evaluated the benefits of MAP control programs when the herd is also affected by mastitis, a common disease causing the largest losses in dairy production. The effect of typically suggested MAP controls were estimated under the assumption that MAP infection increased the rate of clinical mastitis. We evaluated one hundred twenty three control strategies comprising various combinations of testing, culling, and hygiene, and found that the association of paratuberculosis with mastitis alters the ranking of specific MAP control programs, but only slightly alters the cost-benefit difference of particular MAP control components, as measured by the distribution of net present value of a representative U.S. dairy operation. In particular, although testing and culling for MAP resulted in a reduction in MAP incidence, that control led to lower net present value (NPV) per cow. When testing was used, ELISA was more economically beneficial than alternative testing regimes, especially if mastitis was explicitly modeled as more likely in MAP-infected animals, but ELISA testing was only significantly associated with higher NPV if mastitis was not included in the model at all. Additional hygiene was associated with a lower NPV per cow, although it lowered MAP prevalence. Overall, the addition of an increased risk of mastitis in MAP-infected animals did not change model recommendations as much as failing to consider.https://doi.org/10.1371/journal.pone.0217888 |
| spellingShingle | Leslie J Verteramo Chiu Loren W Tauer Yrjo T Gröhn Rebecca L Smith Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study. PLoS ONE |
| title | Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study. |
| title_full | Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study. |
| title_fullStr | Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study. |
| title_full_unstemmed | Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study. |
| title_short | Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study. |
| title_sort | mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle a stochastic modeling study |
| url | https://doi.org/10.1371/journal.pone.0217888 |
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