Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study
Purpose This study aimed to investigate the correlation between the fat signal fraction (FF) of the fatdominant bone tissue of the knee joint, measured using the MRI Dixon method (DIXON) technique, and bone mineral density (BMD). Materials and Methods Among the patients who underwent knee DIXON i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Radiology
2023-03-01
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| Series: | Journal of the Korean Society of Radiology |
| Subjects: |
| _version_ | 1797856511428395008 |
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| author | Sung Hyun An Kyu-Sung Kwack Sunghoon Park Jae Sung Yun Bumhee Park Ji Su Kim |
| author_facet | Sung Hyun An Kyu-Sung Kwack Sunghoon Park Jae Sung Yun Bumhee Park Ji Su Kim |
| author_sort | Sung Hyun An |
| collection | DOAJ |
| description | Purpose This study aimed to investigate the correlation between the fat signal fraction (FF) of the fatdominant
bone tissue of the knee joint, measured using the MRI Dixon method (DIXON) technique,
and bone mineral density (BMD).
Materials and Methods Among the patients who underwent knee DIXON imaging at our institute,
we retrospectively analyzed 93 patients who also underwent dual energy X-ray absorptiometry within
1 year. The FFs of the distal femur metaphyseal (Fm) and proximal tibia metaphyseal (Tm) were calculated
from the DIXON images, and the correlation between FF and BMD was analyzed. Patients were
grouped based on BMD of lumbar spine (L), femoral neck (FN), and common femur (FT) respectively,
and the Kruskal-Wallis H test was performed for FF.
Results We identified a significant negative correlation between TmFF and FN-BMD in the entire patient
group (r = -0.26, p < 0.05). In female patients, TmFF showed a negative correlation with FN-BMD, FT-BMD, and L-BMD (r = -0.38, 0.28 and -0.27, p < 0.05). In male patients, FmFF was negatively correlated
with only FN-BMD and FT-BMD (r = -0.58 and -0.42, p < 0.05). There was a significant difference in
the TmFF between female patients grouped by BMD (p < 0.05). In male patients, there was a significant
difference in FmFF (p < 0.05).
Conclusion Overall, we found that FF and BMD around the knee joints showed a negative correlation.
This suggests the potential of FF measurement using DIXON for BMD screening. |
| first_indexed | 2024-04-09T20:41:33Z |
| format | Article |
| id | doaj.art-d32b1873f03f42d3a560f562250383b9 |
| institution | Directory Open Access Journal |
| issn | 2951-0805 |
| language | English |
| last_indexed | 2024-04-09T20:41:33Z |
| publishDate | 2023-03-01 |
| publisher | The Korean Society of Radiology |
| record_format | Article |
| series | Journal of the Korean Society of Radiology |
| spelling | doaj.art-d32b1873f03f42d3a560f562250383b92023-03-30T01:17:11ZengThe Korean Society of RadiologyJournal of the Korean Society of Radiology2951-08052023-03-0184242744010.3348/jksr.2022.0039Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary StudySung Hyun AnKyu-Sung KwackSunghoon ParkJae Sung YunBumhee ParkJi Su KimPurpose This study aimed to investigate the correlation between the fat signal fraction (FF) of the fatdominant bone tissue of the knee joint, measured using the MRI Dixon method (DIXON) technique, and bone mineral density (BMD). Materials and Methods Among the patients who underwent knee DIXON imaging at our institute, we retrospectively analyzed 93 patients who also underwent dual energy X-ray absorptiometry within 1 year. The FFs of the distal femur metaphyseal (Fm) and proximal tibia metaphyseal (Tm) were calculated from the DIXON images, and the correlation between FF and BMD was analyzed. Patients were grouped based on BMD of lumbar spine (L), femoral neck (FN), and common femur (FT) respectively, and the Kruskal-Wallis H test was performed for FF. Results We identified a significant negative correlation between TmFF and FN-BMD in the entire patient group (r = -0.26, p < 0.05). In female patients, TmFF showed a negative correlation with FN-BMD, FT-BMD, and L-BMD (r = -0.38, 0.28 and -0.27, p < 0.05). In male patients, FmFF was negatively correlated with only FN-BMD and FT-BMD (r = -0.58 and -0.42, p < 0.05). There was a significant difference in the TmFF between female patients grouped by BMD (p < 0.05). In male patients, there was a significant difference in FmFF (p < 0.05). Conclusion Overall, we found that FF and BMD around the knee joints showed a negative correlation. This suggests the potential of FF measurement using DIXON for BMD screening.kneemagnetic resonance imagingbone densitybone mineral densitylipidsosteoporosis |
| spellingShingle | Sung Hyun An Kyu-Sung Kwack Sunghoon Park Jae Sung Yun Bumhee Park Ji Su Kim Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study Journal of the Korean Society of Radiology knee magnetic resonance imaging bone density bone mineral density lipids osteoporosis |
| title | Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study |
| title_full | Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study |
| title_fullStr | Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study |
| title_full_unstemmed | Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study |
| title_short | Correlation Analysis between Fat Fraction and Bone Mineral Density Using the DIXON Method for Fat Dominant Tissue in Knee Joint MRI: A Preliminary Study |
| title_sort | correlation analysis between fat fraction and bone mineral density using the dixon method for fat dominant tissue in knee joint mri a preliminary study |
| topic | knee magnetic resonance imaging bone density bone mineral density lipids osteoporosis |
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