Human innate Mycobacterium tuberculosis-reactive alphabetaTCR+ thymocytes.
The control of Mycobacterium tuberculosis (Mtb) infection is heavily dependent on the adaptive Th1 cellular immune response. Paradoxically, optimal priming of the Th1 response requires activation of priming dendritic cells with Th1 cytokine IFN-gamma. At present, the innate cellular mechanisms requi...
Main Authors: | Marielle C Gold, Heather D Ehlinger, Matthew S Cook, Susan K Smyk-Pearson, Paul T Wille, Ross M Ungerleider, Deborah A Lewinsohn, David M Lewinsohn |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-02-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2242840?pdf=render |
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