The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus
Background: The association between the inflammatory markers and Type 2 Diabetes Mellitus (T2DM) has been widely reported. The epidemiology of T2DM shows a rapid increase in the disease in developing countries. African foods have the potential to reduce the inflammatory markers associated with T2DM....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Human Nutrition & Metabolism |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666149723000531 |
| _version_ | 1797328625908842496 |
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| author | Florence Malongane Wendy N. Phoswa Tendaiishe Berejena |
| author_facet | Florence Malongane Wendy N. Phoswa Tendaiishe Berejena |
| author_sort | Florence Malongane |
| collection | DOAJ |
| description | Background: The association between the inflammatory markers and Type 2 Diabetes Mellitus (T2DM) has been widely reported. The epidemiology of T2DM shows a rapid increase in the disease in developing countries. African foods have the potential to reduce the inflammatory markers associated with T2DM. All the food groups in the African diet possess anti-hyperglycemic, anti-inflammatory, and anti-hypercholesterolemia properties, which are essential in controlling T2DM. Objectives: This study sought to assess the role of indigenous African food groups in preventing and managing T2DM. It examined the anti-inflammatory properties of African food groups in relation to T2DM. Material and methods: A narrative review assessed different African food groups' anti-inflammatory and anti-hyperglycemic activities. A comprehensive literature search was conducted using various scientific databases, which include PubMed, Google Scholar, Medline and books. In vivo and in vitro studies were selected to analyse the effects of the African diet on inflammatory markers associated with T2DM. The review was conducted between February and October 2023. Results: The African vegetables, cereals, tubers, insects and fermented foods reduced the production of inflammatory cytokines such as Tumour Necrosis Factor-alpha (TNF-a), Interleukin 1, (IL-1), Interleukin 6, (IL- 6), Interleukin 8 (IL-8) and inflammatory mediators such as Nitric Oxide (NO). The in vivo and in vitro studies revealed a significant content of α-amylase and α-glycosidase inhibitors in African foods. Inflammation reduction and increased antioxidants were also exhibited in different food groups. However, future studies are needed to compare the anti-inflammatory activities of African foods before and after processing. Conclusion: The anti-hyperglycemic, anti-inflammatory, and anti-hypercholesterolemia properties predominantly exist in all African food groups. A substantial content of compounds identified demonstrated several effects, which include anti-inflammatory, antiglycation, anti-α-amylase, anti- α-glucosidase, anti-lipase, and anti-acetyl cholinesterase. These properties are essential in controlling the inflammatory markers linked to T2DM. |
| first_indexed | 2024-03-08T06:54:23Z |
| format | Article |
| id | doaj.art-d32c8b8529ff4e4cad60ce31ef48c68d |
| institution | Directory Open Access Journal |
| issn | 2666-1497 |
| language | English |
| last_indexed | 2024-03-08T06:54:23Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Nutrition & Metabolism |
| spelling | doaj.art-d32c8b8529ff4e4cad60ce31ef48c68d2024-02-03T06:39:23ZengElsevierHuman Nutrition & Metabolism2666-14972024-03-0135200236The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic MellitusFlorence Malongane0Wendy N. Phoswa1Tendaiishe Berejena2Corresponding author.; Department of Life and Consumer Sciences, University of South Africa (UNISA) Science Campus, Private Bag X6, Florida, Roodepoort, 1710, South AfricaDepartment of Life and Consumer Sciences, University of South Africa (UNISA) Science Campus, Private Bag X6, Florida, Roodepoort, 1710, South AfricaDepartment of Life and Consumer Sciences, University of South Africa (UNISA) Science Campus, Private Bag X6, Florida, Roodepoort, 1710, South AfricaBackground: The association between the inflammatory markers and Type 2 Diabetes Mellitus (T2DM) has been widely reported. The epidemiology of T2DM shows a rapid increase in the disease in developing countries. African foods have the potential to reduce the inflammatory markers associated with T2DM. All the food groups in the African diet possess anti-hyperglycemic, anti-inflammatory, and anti-hypercholesterolemia properties, which are essential in controlling T2DM. Objectives: This study sought to assess the role of indigenous African food groups in preventing and managing T2DM. It examined the anti-inflammatory properties of African food groups in relation to T2DM. Material and methods: A narrative review assessed different African food groups' anti-inflammatory and anti-hyperglycemic activities. A comprehensive literature search was conducted using various scientific databases, which include PubMed, Google Scholar, Medline and books. In vivo and in vitro studies were selected to analyse the effects of the African diet on inflammatory markers associated with T2DM. The review was conducted between February and October 2023. Results: The African vegetables, cereals, tubers, insects and fermented foods reduced the production of inflammatory cytokines such as Tumour Necrosis Factor-alpha (TNF-a), Interleukin 1, (IL-1), Interleukin 6, (IL- 6), Interleukin 8 (IL-8) and inflammatory mediators such as Nitric Oxide (NO). The in vivo and in vitro studies revealed a significant content of α-amylase and α-glycosidase inhibitors in African foods. Inflammation reduction and increased antioxidants were also exhibited in different food groups. However, future studies are needed to compare the anti-inflammatory activities of African foods before and after processing. Conclusion: The anti-hyperglycemic, anti-inflammatory, and anti-hypercholesterolemia properties predominantly exist in all African food groups. A substantial content of compounds identified demonstrated several effects, which include anti-inflammatory, antiglycation, anti-α-amylase, anti- α-glucosidase, anti-lipase, and anti-acetyl cholinesterase. These properties are essential in controlling the inflammatory markers linked to T2DM.http://www.sciencedirect.com/science/article/pii/S2666149723000531African dietsInflammatory markersDiabetes Mellitusassociation |
| spellingShingle | Florence Malongane Wendy N. Phoswa Tendaiishe Berejena The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus Human Nutrition & Metabolism African diets Inflammatory markers Diabetes Mellitus association |
| title | The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus |
| title_full | The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus |
| title_fullStr | The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus |
| title_full_unstemmed | The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus |
| title_short | The effect of indigenous African Diet on inflammatory markers linked to Type 2 Diabetic Mellitus |
| title_sort | effect of indigenous african diet on inflammatory markers linked to type 2 diabetic mellitus |
| topic | African diets Inflammatory markers Diabetes Mellitus association |
| url | http://www.sciencedirect.com/science/article/pii/S2666149723000531 |
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