State of the art <it>de novo </it>assembly of human genomes from massively parallel sequencing data

State of the art <it>de novo </it>assembly of human genomes from massively parallel sequencing data

<p>Abstract</p> <p>Recent studies in human genomes have demonstrated the use of <it>de novo </it>assemblies to identify genetic variations that are difficult for mapping-based approaches. Construction of multiple human genome assemblies is enabled by massively parallel...

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Bibliographic Details
Main Authors: Li Yingrui, Hu Yujie, Bolund Lars, Wang Jun
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Human Genomics
Subjects:
de novo assembly
de Bruijn graph
massively parallel sequencing
Online Access:http://www.humgenomics.com/content/4/4/271

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