Infections of Pathogens in Lesions of Cutaneous Carcinoma
Objective To investigate the lesions and pathogen infections of the inpatients diagnosed as cutaneous carcinoma, and provide the basis of rational drug use for clinicians. Methods For the 88 inpatients with cutaneous carcinoma, secretions were collected from the 41 patients whose lesions were ulcera...
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| Format: | Article |
| Language: | zho |
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Magazine House of Cancer Research on Prevention and Treatment
2019-07-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0083.htm |
| _version_ | 1818304707357048832 |
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| author | MAO Shiwang YAN Yueying FENG Guangdong BU Wenbo ZHAO Liang ZHAI Jianxin FANG Fang |
| author_facet | MAO Shiwang YAN Yueying FENG Guangdong BU Wenbo ZHAO Liang ZHAI Jianxin FANG Fang |
| author_sort | MAO Shiwang |
| collection | DOAJ |
| description | Objective To investigate the lesions and pathogen infections of the inpatients diagnosed as cutaneous carcinoma, and provide the basis of rational drug use for clinicians. Methods For the 88 inpatients with cutaneous carcinoma, secretions were collected from the 41 patients whose lesions were ulcerative. VITEK 2 Compact automatic bacterial identification and susceptibility analysis system were applied to perform species identification and drug resistance testing. Results Thirty-one were positive for the culture of pathogens, among which 18 were Gram-positive bacterium and staphylococcus aureus was the majority; 13 were Gram-negative bacterium and pseudomonas aeruginosa and proteus mirabilis were the majority. The resistant rate of Gram-positive bacterium to macrolide antibiotics was 72.5%. The resistant rate of Gram-negative bacterium to doxycycline reached 100%, and it was also highly resistant to cephalosporin antibiotics. Additionally, four cases of multi-drug resistant bacteria were found. Conclusion Since bacterial infections are prevalent in the ulcerative lesions of cutaneous carcinoma, clinician should perform pre- and post-operative interventions on the basis of strains identification and susceptibility test results. |
| first_indexed | 2024-12-13T06:14:58Z |
| format | Article |
| id | doaj.art-d334de7289cd4036b40877d642e82720 |
| institution | Directory Open Access Journal |
| issn | 1000-8578 1000-8578 |
| language | zho |
| last_indexed | 2024-12-13T06:14:58Z |
| publishDate | 2019-07-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj.art-d334de7289cd4036b40877d642e827202022-12-21T23:57:00ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782019-07-0146761461610.3971/j.issn.1000-8578.2019.19.00838578.2019.19.0083Infections of Pathogens in Lesions of Cutaneous CarcinomaMAO Shiwang0YAN Yueying1FENG Guangdong2BU Wenbo3ZHAO Liang4ZHAI Jianxin5FANG Fang6Department of Dermatology, The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi 214002, ChinaDepartment of Dermatology, Heze Municipal Hospital, Heze 274031, ChinaDepartment of Dermatology, The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi 214002, ChinaDepartment of Dermatological Surgery, Institute of Dermatology and Hospital for Skin Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Nanjing 210042, ChinaDepartment of Dermatological Surgery, Institute of Dermatology and Hospital for Skin Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Nanjing 210042, ChinaDepartment of Dermatology, The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi 214002, ChinaDepartment of Dermatological Surgery, Institute of Dermatology and Hospital for Skin Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Nanjing 210042, ChinaObjective To investigate the lesions and pathogen infections of the inpatients diagnosed as cutaneous carcinoma, and provide the basis of rational drug use for clinicians. Methods For the 88 inpatients with cutaneous carcinoma, secretions were collected from the 41 patients whose lesions were ulcerative. VITEK 2 Compact automatic bacterial identification and susceptibility analysis system were applied to perform species identification and drug resistance testing. Results Thirty-one were positive for the culture of pathogens, among which 18 were Gram-positive bacterium and staphylococcus aureus was the majority; 13 were Gram-negative bacterium and pseudomonas aeruginosa and proteus mirabilis were the majority. The resistant rate of Gram-positive bacterium to macrolide antibiotics was 72.5%. The resistant rate of Gram-negative bacterium to doxycycline reached 100%, and it was also highly resistant to cephalosporin antibiotics. Additionally, four cases of multi-drug resistant bacteria were found. Conclusion Since bacterial infections are prevalent in the ulcerative lesions of cutaneous carcinoma, clinician should perform pre- and post-operative interventions on the basis of strains identification and susceptibility test results.http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0083.htmcutaneous carcinomapathogensdrug-susceptibilitymulti-drug resistance |
| spellingShingle | MAO Shiwang YAN Yueying FENG Guangdong BU Wenbo ZHAO Liang ZHAI Jianxin FANG Fang Infections of Pathogens in Lesions of Cutaneous Carcinoma Zhongliu Fangzhi Yanjiu cutaneous carcinoma pathogens drug-susceptibility multi-drug resistance |
| title | Infections of Pathogens in Lesions of Cutaneous Carcinoma |
| title_full | Infections of Pathogens in Lesions of Cutaneous Carcinoma |
| title_fullStr | Infections of Pathogens in Lesions of Cutaneous Carcinoma |
| title_full_unstemmed | Infections of Pathogens in Lesions of Cutaneous Carcinoma |
| title_short | Infections of Pathogens in Lesions of Cutaneous Carcinoma |
| title_sort | infections of pathogens in lesions of cutaneous carcinoma |
| topic | cutaneous carcinoma pathogens drug-susceptibility multi-drug resistance |
| url | http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0083.htm |
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