Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage

Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage

Methylmercury (MeHg) is a ubiquitous environmental pollutant, which can cross the placenta and blood brain barrier, thus affecting fetal growth and development. Although previous studies have demonstrated that MeHg induces endoplasmic reticulum (ER) stress in rat cerebral cortex and primary neurons,...

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Bibliographic Details
Main Authors: Jingjing Pan, Xiaoyang Li, Haihui Liu, Chen Wang, Si Xu, Bin Xu, Yu Deng, Tianyao Yang, Wei Liu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Methylmercury
Neurodevelopment
Endoplasmic reticulum stress
CHOP
DNA methylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322009393

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