Clinical, genetic, and epidemiological survey of Polish children and adolescents with severe obesity: A study protocol of the Polish–German study project on severe early-onset obesity

Clinical, genetic, and epidemiological survey of Polish children and adolescents with severe obesity: A study protocol of the Polish–German study project on severe early-onset obesity

Severe early-onset obesity (SEOO) in children is a common feature of monogenic obesity. Nowadays, mutations in at least 50 genes are known to be related to monogenic obesity, and many others are tested. Part of them is involved in the leptin–proopiomelanocortin pathway. The aim of the project is to...

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Bibliographic Details
Main Authors: Magdalena Mierzwa, Mirosław Bik-Multanowski, Michael B. Ranke, Stephanie Brandt, Bertram Flehmig, Ewa Małecka-Tendera, Artur Mazur, Elżbieta Petriczko, Martin Wabitsch, Małgorzata Wójcik, Agnieszka Zachurzok
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
monogenic obesity
leptin
severe early onset obesity
children
adolescents
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.972174/full

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