Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 mg/100 gr of tissue. Data associated with clinical variables and paralytic shellfish tox...
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| Format: | Article |
| Language: | English |
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BMC
2005-01-01
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| Series: | Biological Research |
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| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000200009 |
| _version_ | 1818899055720267776 |
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| author | CARLOS GARCÍA MARCELO LAGOS DOMINIQUE TRUAN KARINNA LATTES OMAR VÉJAR BEATRIZ CHAMORRO VERÓNICA IGLESIAS DARÍO ANDRINOLO NÉSTOR LAGOS |
| author_facet | CARLOS GARCÍA MARCELO LAGOS DOMINIQUE TRUAN KARINNA LATTES OMAR VÉJAR BEATRIZ CHAMORRO VERÓNICA IGLESIAS DARÍO ANDRINOLO NÉSTOR LAGOS |
| author_sort | CARLOS GARCÍA |
| collection | DOAJ |
| description | This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 mg/100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample |
| first_indexed | 2024-12-19T19:41:53Z |
| format | Article |
| id | doaj.art-d343f6878cf64163b7721ae187fd666a |
| institution | Directory Open Access Journal |
| issn | 0716-9760 0717-6287 |
| language | English |
| last_indexed | 2024-12-19T19:41:53Z |
| publishDate | 2005-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Biological Research |
| spelling | doaj.art-d343f6878cf64163b7721ae187fd666a2022-12-21T20:08:14ZengBMCBiological Research0716-97600717-62872005-01-01382-3197205Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urineCARLOS GARCÍAMARCELO LAGOSDOMINIQUE TRUANKARINNA LATTESOMAR VÉJARBEATRIZ CHAMORROVERÓNICA IGLESIASDARÍO ANDRINOLONÉSTOR LAGOSThis study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 mg/100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract samplehttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000200009paralytic shellfish poisoningPSP human intoxicationChilean fjords |
| spellingShingle | CARLOS GARCÍA MARCELO LAGOS DOMINIQUE TRUAN KARINNA LATTES OMAR VÉJAR BEATRIZ CHAMORRO VERÓNICA IGLESIAS DARÍO ANDRINOLO NÉSTOR LAGOS Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine Biological Research paralytic shellfish poisoning PSP human intoxication Chilean fjords |
| title | Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_full | Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_fullStr | Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_full_unstemmed | Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_short | Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine |
| title_sort | human intoxication with paralytic shellfish toxins clinical parameters and toxin analysis in plasma and urine |
| topic | paralytic shellfish poisoning PSP human intoxication Chilean fjords |
| url | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000200009 |
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