Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study
Abstract Objective The objective of this study is to investigate the incidence and risk factors for stone formation and recurrence in patients with neurogenic lower urinary tract dysfunction (NLUTD) in a real‐world cohort. Materials and methods A retrospective cohort study was conducted on all patie...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-03-01
|
| Series: | BJUI Compass |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/bco2.330 |
| _version_ | 1797265487328968704 |
|---|---|
| author | Sandra Möhr Saskia Fassbind Brigitta Gahl Hans‐Helge Seifert Kathrin Bausch |
| author_facet | Sandra Möhr Saskia Fassbind Brigitta Gahl Hans‐Helge Seifert Kathrin Bausch |
| author_sort | Sandra Möhr |
| collection | DOAJ |
| description | Abstract Objective The objective of this study is to investigate the incidence and risk factors for stone formation and recurrence in patients with neurogenic lower urinary tract dysfunction (NLUTD) in a real‐world cohort. Materials and methods A retrospective cohort study was conducted on all patients with NLUTD who underwent bladder stone treatment between 2010 and 2022. Univariate and multivariate Cox models were used to identify the potential risk factors for stone recurrence. Results Among 114 patients included in the study, 30% experienced stone recurrence. The most common stone components were carbonate apatite phosphate and magnesium ammonium phosphate. The overall recurrence rate was 14 cases per 100 patient years. Neurogenic detrusor overactivity had the highest recurrence rate. Risk factors for stone recurrence in the multivariate analysis were intermittent and suprapubic catheterization, and recurrent urinary tract infection (rUTI). Conclusions Patients experienced multiple bladder stone recurrences. Close monitoring of bladder pressure and UTI with restrictive catheter application may reduce the risk of stone recurrence. |
| first_indexed | 2024-04-25T00:45:35Z |
| format | Article |
| id | doaj.art-d348883f0856474e87e66d3b569d4439 |
| institution | Directory Open Access Journal |
| issn | 2688-4526 |
| language | English |
| last_indexed | 2024-04-25T00:45:35Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | BJUI Compass |
| spelling | doaj.art-d348883f0856474e87e66d3b569d44392024-03-12T04:55:08ZengWileyBJUI Compass2688-45262024-03-015335936510.1002/bco2.330Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world studySandra Möhr0Saskia Fassbind1Brigitta Gahl2Hans‐Helge Seifert3Kathrin Bausch4Department of Urology REHAB Basel Basel SwitzerlandDepartment of Urology REHAB Basel Basel SwitzerlandSurgical Outcome Research Center Basel University Hospital of Basel Basel SwitzerlandUniversity of Basel Basel SwitzerlandUniversity of Basel Basel SwitzerlandAbstract Objective The objective of this study is to investigate the incidence and risk factors for stone formation and recurrence in patients with neurogenic lower urinary tract dysfunction (NLUTD) in a real‐world cohort. Materials and methods A retrospective cohort study was conducted on all patients with NLUTD who underwent bladder stone treatment between 2010 and 2022. Univariate and multivariate Cox models were used to identify the potential risk factors for stone recurrence. Results Among 114 patients included in the study, 30% experienced stone recurrence. The most common stone components were carbonate apatite phosphate and magnesium ammonium phosphate. The overall recurrence rate was 14 cases per 100 patient years. Neurogenic detrusor overactivity had the highest recurrence rate. Risk factors for stone recurrence in the multivariate analysis were intermittent and suprapubic catheterization, and recurrent urinary tract infection (rUTI). Conclusions Patients experienced multiple bladder stone recurrences. Close monitoring of bladder pressure and UTI with restrictive catheter application may reduce the risk of stone recurrence.https://doi.org/10.1002/bco2.330calcium phosphaterisk factorsspinal cord injuryurinary tract infectionsurolithiasis |
| spellingShingle | Sandra Möhr Saskia Fassbind Brigitta Gahl Hans‐Helge Seifert Kathrin Bausch Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study BJUI Compass calcium phosphate risk factors spinal cord injury urinary tract infections urolithiasis |
| title | Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study |
| title_full | Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study |
| title_fullStr | Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study |
| title_full_unstemmed | Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study |
| title_short | Risk factors of bladder stones in neurogenic lower urinary tract dysfunction: A real‐world study |
| title_sort | risk factors of bladder stones in neurogenic lower urinary tract dysfunction a real world study |
| topic | calcium phosphate risk factors spinal cord injury urinary tract infections urolithiasis |
| url | https://doi.org/10.1002/bco2.330 |
| work_keys_str_mv | AT sandramohr riskfactorsofbladderstonesinneurogeniclowerurinarytractdysfunctionarealworldstudy AT saskiafassbind riskfactorsofbladderstonesinneurogeniclowerurinarytractdysfunctionarealworldstudy AT brigittagahl riskfactorsofbladderstonesinneurogeniclowerurinarytractdysfunctionarealworldstudy AT hanshelgeseifert riskfactorsofbladderstonesinneurogeniclowerurinarytractdysfunctionarealworldstudy AT kathrinbausch riskfactorsofbladderstonesinneurogeniclowerurinarytractdysfunctionarealworldstudy |