Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam

Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism pa...

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Main Authors: Nguyen Thi Ngoc Lan, Hoang Thi Kim Lien, Le B. Tung, Martien W. Borgdorff, Kristin Kremer, Dick van Soolingen
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2003-12-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/9/12/03-0169_article
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author Nguyen Thi Ngoc Lan
Hoang Thi Kim Lien
Le B. Tung
Martien W. Borgdorff
Kristin Kremer
Dick van Soolingen
author_facet Nguyen Thi Ngoc Lan
Hoang Thi Kim Lien
Le B. Tung
Martien W. Borgdorff
Kristin Kremer
Dick van Soolingen
author_sort Nguyen Thi Ngoc Lan
collection DOAJ
description Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).
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spelling doaj.art-d34af4e8d68f449bbef211058c1560832022-12-21T22:36:20ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592003-12-019121633163510.3201/eid0912.030169Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, VietnamNguyen Thi Ngoc LanHoang Thi Kim LienLe B. TungMartien W. BorgdorffKristin KremerDick van SoolingenAmong 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).https://wwwnc.cdc.gov/eid/article/9/12/03-0169_articleMycobacterium tuberculosisepidemiologymultidrug resistancetreatment failureBeijing genotypeVietnam
spellingShingle Nguyen Thi Ngoc Lan
Hoang Thi Kim Lien
Le B. Tung
Martien W. Borgdorff
Kristin Kremer
Dick van Soolingen
Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
Emerging Infectious Diseases
Mycobacterium tuberculosis
epidemiology
multidrug resistance
treatment failure
Beijing genotype
Vietnam
title Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
title_full Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
title_fullStr Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
title_full_unstemmed Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
title_short Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
title_sort mycobacterium tuberculosis beijing genotype and risk for treatment failure and relapse vietnam
topic Mycobacterium tuberculosis
epidemiology
multidrug resistance
treatment failure
Beijing genotype
Vietnam
url https://wwwnc.cdc.gov/eid/article/9/12/03-0169_article
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