Transfer RNA-derived small RNAs and their potential roles in the therapeutic heterogeneity of sacubitril/valsartan in heart failure patients after acute myocardial infarction

Transfer RNA-derived small RNAs and their potential roles in the therapeutic heterogeneity of sacubitril/valsartan in heart failure patients after acute myocardial infarction

BackgroundIt has been reported that sacubitril/valsartan can improve cardiac function in acute myocardial infarction (AMI) patients complicated by heart failure (HF). However, a number of patients cannot be treated successfully; this phenomenon is called sacubitril/valsartan resistance (SVR), and th...

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Bibliographic Details
Main Authors: Jia Su, Ji Cheng, Yingchu Hu, Qinglin Yu, Zhenwei Li, Jiyi Li, Nan Zheng, Zhaoxia Zhang, Jin Yang, Xiaojing Li, Zeqin Zhang, Yong Wang, Keqi Zhu, Weiping Du, Xiaomin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
tsRNA
expression profile
sacubitril/valsartan
lipid and atherosclerosis signal pathway
heart failure
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.961700/full

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