Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect?

Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect?

Abstract Background Levels of the biomarkers amyloid-β 1–42 (Aβ42), tau and phosphorylated tau (p-tau) are decreased in the cerebrospinal fluid (CSF) of patients with idiopathic normal pressure hydrocephalus (iNPH). The mechanism behind this is unknown, but one potential explanation is dilution by e...

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Bibliographic Details
Main Authors: Simon Lidén, Dan Farahmand, Katarina Laurell
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Normal Pressure Hydrocephalus
Ventricular volume
Amyloid-β
Tau
Cerebrospinal fluid
Online Access:https://doi.org/10.1186/s12987-022-00353-9

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