HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach
Abstract Purpose The HyperArc VMAT (HA-VMAT) planning approach was newly developed to fulfill the demands of dose delivery for brain metastases stereotactic radiosurgery. We compared the dosimetric parameters of the HA-VMAT plan with those of the conventional VMAT (C-VMAT). Material and methods For...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-01-01
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| Series: | Radiation Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13014-017-0948-z |
| _version_ | 1828870334297669632 |
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| author | Shingo Ohira Yoshihiro Ueda Yuichi Akino Misaki Hashimoto Akira Masaoka Takero Hirata Masayoshi Miyazaki Masahiko Koizumi Teruki Teshima |
| author_facet | Shingo Ohira Yoshihiro Ueda Yuichi Akino Misaki Hashimoto Akira Masaoka Takero Hirata Masayoshi Miyazaki Masahiko Koizumi Teruki Teshima |
| author_sort | Shingo Ohira |
| collection | DOAJ |
| description | Abstract Purpose The HyperArc VMAT (HA-VMAT) planning approach was newly developed to fulfill the demands of dose delivery for brain metastases stereotactic radiosurgery. We compared the dosimetric parameters of the HA-VMAT plan with those of the conventional VMAT (C-VMAT). Material and methods For 23 patients (1–4 brain metastases), C-VMAT and HA-VMAT plans with a prescription dose of 20–24 Gy were retrospectively generated, and dosimetric parameters for PTV (homogeneity index, HI; conformity index, CI; gradient index, GI) and brain tissue (V2Gy-V16Gy) were evaluated. Subsequently, the physical characteristics (modulation complexity score for VMAT, MCSV; Monitor unit, MU) of both treatment approaches were compared. Results HA-VMAT provided higher HI (1.41 ± 0.07 vs. 1.24 ± 0.07, p < 0.01), CI (0.93 ± 0.02 vs. 0.90 ± 0.05, p = 0.01) and lower GI (3.06 ± 0.42 vs. 3.91 ± 0.55, p < 0.01) values. Moderate-to-low dose spreads (V4Gy-V16Gy) were significantly reduced (p < 0.01) in the HA-VMAT plan over that of C-VMAT. HA-VMAT plans resulted in more complex MLC patterns (lower MCSV, p < 0.01) and higher MU (p < 0.01). Conclusions HA-VMAT plans provided significantly higher conformity and rapid dose falloff with respect to the C-VMAT plans. |
| first_indexed | 2024-12-13T06:08:48Z |
| format | Article |
| id | doaj.art-d3520a8744f64548b41c30177c2fb201 |
| institution | Directory Open Access Journal |
| issn | 1748-717X |
| language | English |
| last_indexed | 2024-12-13T06:08:48Z |
| publishDate | 2018-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Radiation Oncology |
| spelling | doaj.art-d3520a8744f64548b41c30177c2fb2012022-12-21T23:57:09ZengBMCRadiation Oncology1748-717X2018-01-011311910.1186/s13014-017-0948-zHyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approachShingo Ohira0Yoshihiro Ueda1Yuichi Akino2Misaki Hashimoto3Akira Masaoka4Takero Hirata5Masayoshi Miyazaki6Masahiko Koizumi7Teruki Teshima8Department of Radiation Oncology, Osaka International Cancer InstituteDepartment of Radiation Oncology, Osaka International Cancer InstituteDivision of Medical Physics, Oncology Center, Osaka University HospitalDepartment of Radiation Oncology, Yao Municipal HospitalDepartment of Radiation Oncology, Osaka International Cancer InstituteDepartment of Radiation Oncology, Osaka International Cancer InstituteDepartment of Radiation Oncology, Osaka International Cancer InstituteDepartment of Medical Physics and Engineering, Osaka University Graduate School of MedicineDepartment of Radiation Oncology, Osaka International Cancer InstituteAbstract Purpose The HyperArc VMAT (HA-VMAT) planning approach was newly developed to fulfill the demands of dose delivery for brain metastases stereotactic radiosurgery. We compared the dosimetric parameters of the HA-VMAT plan with those of the conventional VMAT (C-VMAT). Material and methods For 23 patients (1–4 brain metastases), C-VMAT and HA-VMAT plans with a prescription dose of 20–24 Gy were retrospectively generated, and dosimetric parameters for PTV (homogeneity index, HI; conformity index, CI; gradient index, GI) and brain tissue (V2Gy-V16Gy) were evaluated. Subsequently, the physical characteristics (modulation complexity score for VMAT, MCSV; Monitor unit, MU) of both treatment approaches were compared. Results HA-VMAT provided higher HI (1.41 ± 0.07 vs. 1.24 ± 0.07, p < 0.01), CI (0.93 ± 0.02 vs. 0.90 ± 0.05, p = 0.01) and lower GI (3.06 ± 0.42 vs. 3.91 ± 0.55, p < 0.01) values. Moderate-to-low dose spreads (V4Gy-V16Gy) were significantly reduced (p < 0.01) in the HA-VMAT plan over that of C-VMAT. HA-VMAT plans resulted in more complex MLC patterns (lower MCSV, p < 0.01) and higher MU (p < 0.01). Conclusions HA-VMAT plans provided significantly higher conformity and rapid dose falloff with respect to the C-VMAT plans.http://link.springer.com/article/10.1186/s13014-017-0948-zBrain metastasesStereotactic radiosurgeryVMATHyperArcDosimetric parameter |
| spellingShingle | Shingo Ohira Yoshihiro Ueda Yuichi Akino Misaki Hashimoto Akira Masaoka Takero Hirata Masayoshi Miyazaki Masahiko Koizumi Teruki Teshima HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach Radiation Oncology Brain metastases Stereotactic radiosurgery VMAT HyperArc Dosimetric parameter |
| title | HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach |
| title_full | HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach |
| title_fullStr | HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach |
| title_full_unstemmed | HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach |
| title_short | HyperArc VMAT planning for single and multiple brain metastases stereotactic radiosurgery: a new treatment planning approach |
| title_sort | hyperarc vmat planning for single and multiple brain metastases stereotactic radiosurgery a new treatment planning approach |
| topic | Brain metastases Stereotactic radiosurgery VMAT HyperArc Dosimetric parameter |
| url | http://link.springer.com/article/10.1186/s13014-017-0948-z |
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