COVID-19 related acute limb ischaemia: A case series

COVID-19 infection or vaccination is rarely associated with arterial occlusive disease of the extremities. The surgical department of a hospital in Johor, Malaysia, recorded a significant increase in the number of COVID-19-related acute limb ischaemia when the rates of COVID-19 were high both locall...

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Main Authors: Jih Huei Tan, Henry Chor Lip Tan, Addy Aun Wei Ang, Ida Arinah Mahadi, Zi Huan Khoo, Po Hong Tan, Mohamad Yuzaidi, Rizal Imran Alwi, Tuan Nur Azmah Tuan Mat
Format: Article
Language:English
Published: Academy of Family Physicians of Malaysia 2023-03-01
Series:Malaysian Family Physician
Subjects:
Online Access:https://e-mfp.org/wp-content/uploads/18.8R2CRCaseseriesofCOVID-19.pdf
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author Jih Huei Tan
Henry Chor Lip Tan
Addy Aun Wei Ang
Ida Arinah Mahadi
Zi Huan Khoo
Po Hong Tan
Mohamad Yuzaidi
Rizal Imran Alwi
Tuan Nur Azmah Tuan Mat
author_facet Jih Huei Tan
Henry Chor Lip Tan
Addy Aun Wei Ang
Ida Arinah Mahadi
Zi Huan Khoo
Po Hong Tan
Mohamad Yuzaidi
Rizal Imran Alwi
Tuan Nur Azmah Tuan Mat
author_sort Jih Huei Tan
collection DOAJ
description COVID-19 infection or vaccination is rarely associated with arterial occlusive disease of the extremities. The surgical department of a hospital in Johor, Malaysia, recorded a significant increase in the number of COVID-19-related acute limb ischaemia when the rates of COVID-19 were high both locally and internationally. The clinical presentation and management of acute limb ischaemia associated with COVID-19 infection or vaccination are largely underreported in Johor. Herein, we report a case series of 12 patients managed with strategies ranging from purely anticoagulation to catheter-directed thrombolysis and surgical embolectomy. This case series describes the clinical presentation, risk profiles, treatment approaches and limb outcomes of the patients. The amputation rate was high in view of unfavourable factors, including delayed presentation, high-risk factors and severe COVID-19. Three cases of potential COVID-19 vaccine-related acute limb ischaemia were included. COVID-19-related acute limb ischaemia can be minimised with heightened alert, preemptive optimisation with proper hydration and consideration for early prophylactic anticoagulation in high-risk cases.
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spelling doaj.art-d357045539b342d8aff4edf2369509fa2023-05-01T16:41:41ZengAcademy of Family Physicians of MalaysiaMalaysian Family Physician1985-207X1985-22742023-03-0118810.51866/cr.168COVID-19 related acute limb ischaemia: A case seriesJih Huei TanHenry Chor Lip TanAddy Aun Wei AngIda Arinah MahadiZi Huan KhooPo Hong TanMohamad YuzaidiRizal Imran AlwiTuan Nur Azmah Tuan MatCOVID-19 infection or vaccination is rarely associated with arterial occlusive disease of the extremities. The surgical department of a hospital in Johor, Malaysia, recorded a significant increase in the number of COVID-19-related acute limb ischaemia when the rates of COVID-19 were high both locally and internationally. The clinical presentation and management of acute limb ischaemia associated with COVID-19 infection or vaccination are largely underreported in Johor. Herein, we report a case series of 12 patients managed with strategies ranging from purely anticoagulation to catheter-directed thrombolysis and surgical embolectomy. This case series describes the clinical presentation, risk profiles, treatment approaches and limb outcomes of the patients. The amputation rate was high in view of unfavourable factors, including delayed presentation, high-risk factors and severe COVID-19. Three cases of potential COVID-19 vaccine-related acute limb ischaemia were included. COVID-19-related acute limb ischaemia can be minimised with heightened alert, preemptive optimisation with proper hydration and consideration for early prophylactic anticoagulation in high-risk cases.https://e-mfp.org/wp-content/uploads/18.8R2CRCaseseriesofCOVID-19.pdfcovid-19limb ischaemiaarterial occlusive diseasethrombolysis
spellingShingle Jih Huei Tan
Henry Chor Lip Tan
Addy Aun Wei Ang
Ida Arinah Mahadi
Zi Huan Khoo
Po Hong Tan
Mohamad Yuzaidi
Rizal Imran Alwi
Tuan Nur Azmah Tuan Mat
COVID-19 related acute limb ischaemia: A case series
Malaysian Family Physician
covid-19
limb ischaemia
arterial occlusive disease
thrombolysis
title COVID-19 related acute limb ischaemia: A case series
title_full COVID-19 related acute limb ischaemia: A case series
title_fullStr COVID-19 related acute limb ischaemia: A case series
title_full_unstemmed COVID-19 related acute limb ischaemia: A case series
title_short COVID-19 related acute limb ischaemia: A case series
title_sort covid 19 related acute limb ischaemia a case series
topic covid-19
limb ischaemia
arterial occlusive disease
thrombolysis
url https://e-mfp.org/wp-content/uploads/18.8R2CRCaseseriesofCOVID-19.pdf
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