Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog
Abstract A 3‐year‐old, 3.5 kg, female spayed Pomeranian was referred due to persistent vomiting, anorexia, polyuria and polydipsia, 7 days after receiving general anaesthetic for a medial patellar luxation correction. Physical examination revealed lethargy, tachypnoea and 7% dehydration. Complete bl...
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| Format: | Article |
| Language: | English |
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Wiley
2023-07-01
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| Series: | Veterinary Medicine and Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/vms3.1165 |
| _version_ | 1797776621300613120 |
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| author | Dayoung Ku Dohee Lee Taesik Yun Yoonhoi Koo Yeon Chae Dongjoon Choi Minseok Choi Byeong‐Teck Kang Mhan‐Pyo Yang Hakhyun Kim |
| author_facet | Dayoung Ku Dohee Lee Taesik Yun Yoonhoi Koo Yeon Chae Dongjoon Choi Minseok Choi Byeong‐Teck Kang Mhan‐Pyo Yang Hakhyun Kim |
| author_sort | Dayoung Ku |
| collection | DOAJ |
| description | Abstract A 3‐year‐old, 3.5 kg, female spayed Pomeranian was referred due to persistent vomiting, anorexia, polyuria and polydipsia, 7 days after receiving general anaesthetic for a medial patellar luxation correction. Physical examination revealed lethargy, tachypnoea and 7% dehydration. Complete blood count and serum chemistry results were unremarkable, and venous blood gas analysis revealed hypokalaemia and hyperchloraemic metabolic acidosis with a normal anion gap. Urinalysis revealed a urine specific gravity (USG) of 1.005, pH of 7.0 and proteinuria, and the bacterial culture was negative. Based on these results, the dog was diagnosed with distal renal tubular acidosis, and potassium citrate was prescribed to correct metabolic acidosis. In addition, concurrent diabetes insipidus (DI) was suspected because the dog showed persistent polyuria, polydipsia and a USG below 1.006 despite dehydration. After 3 days of initial treatment, acidosis was corrected, and vomiting resolved. Desmopressin acetate and hydrochlorothiazide were also prescribed for DI, but the USG was not normalized. Based on the insignificant therapeutic response, nephrogenic DI was highly suspected. DI was resolved after 24 days. This case report describes the concomitant presence of RTA and DI in a dog after general anaesthesia. |
| first_indexed | 2024-03-12T22:52:28Z |
| format | Article |
| id | doaj.art-d358e5a09bc241b2a79018172b890249 |
| institution | Directory Open Access Journal |
| issn | 2053-1095 |
| language | English |
| last_indexed | 2024-03-12T22:52:28Z |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj.art-d358e5a09bc241b2a79018172b8902492023-07-20T08:09:46ZengWileyVeterinary Medicine and Science2053-10952023-07-01941483148710.1002/vms3.1165Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dogDayoung Ku0Dohee Lee1Taesik Yun2Yoonhoi Koo3Yeon Chae4Dongjoon Choi5Minseok Choi6Byeong‐Teck Kang7Mhan‐Pyo Yang8Hakhyun Kim9Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaLaboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungbuk National University Cheongju Chungbuk Republic of KoreaAbstract A 3‐year‐old, 3.5 kg, female spayed Pomeranian was referred due to persistent vomiting, anorexia, polyuria and polydipsia, 7 days after receiving general anaesthetic for a medial patellar luxation correction. Physical examination revealed lethargy, tachypnoea and 7% dehydration. Complete blood count and serum chemistry results were unremarkable, and venous blood gas analysis revealed hypokalaemia and hyperchloraemic metabolic acidosis with a normal anion gap. Urinalysis revealed a urine specific gravity (USG) of 1.005, pH of 7.0 and proteinuria, and the bacterial culture was negative. Based on these results, the dog was diagnosed with distal renal tubular acidosis, and potassium citrate was prescribed to correct metabolic acidosis. In addition, concurrent diabetes insipidus (DI) was suspected because the dog showed persistent polyuria, polydipsia and a USG below 1.006 despite dehydration. After 3 days of initial treatment, acidosis was corrected, and vomiting resolved. Desmopressin acetate and hydrochlorothiazide were also prescribed for DI, but the USG was not normalized. Based on the insignificant therapeutic response, nephrogenic DI was highly suspected. DI was resolved after 24 days. This case report describes the concomitant presence of RTA and DI in a dog after general anaesthesia.https://doi.org/10.1002/vms3.1165caninedehydrationhyposthenuriakidneyvomiting |
| spellingShingle | Dayoung Ku Dohee Lee Taesik Yun Yoonhoi Koo Yeon Chae Dongjoon Choi Minseok Choi Byeong‐Teck Kang Mhan‐Pyo Yang Hakhyun Kim Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog Veterinary Medicine and Science canine dehydration hyposthenuria kidney vomiting |
| title | Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog |
| title_full | Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog |
| title_fullStr | Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog |
| title_full_unstemmed | Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog |
| title_short | Transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog |
| title_sort | transient distal renal tubular acidosis with nephrogenic diabetes insipidus after general anaesthesia in a dog |
| topic | canine dehydration hyposthenuria kidney vomiting |
| url | https://doi.org/10.1002/vms3.1165 |
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