Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: Cumulative evidence for future cardioprotective strategies

Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: Cumulative evidence for future cardioprotective strategies

Cardiomyocyte death is one of the major mechanisms contributing to the development of myocardial infarction (MI) and myocardial ischemia/reperfusion (MI/R) injury. Due to the limited regenerative ability of cardiomyocytes, understanding the mechanisms of cardiomyocyte death is necessary. Pyroptosis,...

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Bibliographic Details
Main Authors: Panat Yanpiset, Chayodom Maneechote, Sirawit Sriwichaiin, Natthaphat Siri-Angkul, Siriporn C. Chattipakorn, Nipon Chattipakorn
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Pyroptosis
Gasdermin D
Heart
Ischemia
Ischemia–reperfusion injury
Myocardial infarction
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522003422

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