Analytical Evaluation of an NGS Testing Method for Routine Molecular Diagnostics on Melanoma Formalin-Fixed, Paraffin-Embedded Tumor-Derived DNA

Analytical Evaluation of an NGS Testing Method for Routine Molecular Diagnostics on Melanoma Formalin-Fixed, Paraffin-Embedded Tumor-Derived DNA

Next Generation Sequencing (NGS) is a promising tool for the improvement of tumor molecular profiling in view of the identification of a personalized treatment in oncologic patients. To verify the potentiality of a targeted NGS (Ion AmpliSeq™ Cancer Hotspot Panel v2), selected melanoma sam...

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Bibliographic Details
Main Authors: Irene Mancini, Lisa Simi, Francesca Salvianti, Francesca Castiglione, Gemma Sonnati, Pamela Pinzani
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Diagnostics
Subjects:
melanoma
next generation sequencing
BRAF V-raf murine sarcoma viral oncogene homolog B
somatic mutation
sequenom MassARRAY system
Online Access:https://www.mdpi.com/2075-4418/9/3/117

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