Elucidating the Mechanism of Agrimonolide in Treating Colon Cancer Based on Network Pharmacology

Elucidating the Mechanism of Agrimonolide in Treating Colon Cancer Based on Network Pharmacology

Lei Yu, Yun Gai Department of Oncology I, Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai City, People’s Republic of ChinaCorrespondence: Yun Gai, Department of Oncology I, Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, No...

Full description

Bibliographic Details
Main Authors:	Yu L, Gai Y
Format:	Article
Language:	English
Published:	Dove Medical Press 2023-07-01
Series:	Drug Design, Development and Therapy
Subjects:	colon cancer agrimonolide network pharmacology pi3k/akt/mtor pathway in vivo
Online Access:	https://www.dovepress.com/elucidating-the-mechanism-of-agrimonolide-in-treating-colon-cancer-bas-peer-reviewed-fulltext-article-DDDT

Similar Items

Current Progress and Outlook for Agrimonolide: A Promising Bioactive Compound from <i>Agrimonia pilosa</i> Ledeb.
by: Ting Huang, et al.
Published: (2023-01-01)

Network pharmacology based investigation on the mechanism of tetrandrine against breast cancer
by: Bhagya N
Published: (2023-02-01)

A study on the anti-osteoporosis mechanism of isopsoralen based on network pharmacology and molecular experiments
by: Jian Wang, et al.
Published: (2023-04-01)

Mechanisms of Actinidia chinensis Planch in treating colon cancer based on the integration of network pharmacology, molecular docking, and experimental verification
by: Jin-Fang Chen, et al.
Published: (2023-12-01)

Investigating the Mechanisms of Bisdemethoxycurcumin in Ulcerative Colitis: Network Pharmacology and Experimental Verification
by: Huihuan Wu, et al.
Published: (2022-12-01)

Elucidation of the mechanism of action of ailanthone in the treatment of colorectal cancer: integration of network pharmacology, bioinformatics analysis and experimental validation
by: Shanbo Ma, et al.
Published: (2024-02-01)

PI3K/Akt/mTOR Signaling Pathway in Blood Malignancies—New Therapeutic Possibilities
by: Wojciech Wiese, et al.
Published: (2023-11-01)

Homogeneous Polyporus polysaccharide exerts anti-bladder cancer effects via autophagy induction
by: Siwan Luo, et al.
Published: (2024-12-01)

Effects of LAIR‐1 on hepatocellular carcinoma cell proliferation and invasion via PI3K‐AKT‐mTOR pathway regulation
by: Ti Zhou, et al.
Published: (2023-08-01)

Elucidating Drug-Like Compounds and Potential Mechanisms of Corn Silk (<i>Stigma Maydis</i>) against Obesity: A Network Pharmacology Study
by: Ki-Kwang Oh, et al.
Published: (2021-11-01)

Molecular Mechanism of Inhibition of Cell Proliferation: An In Silico Study of the Active Compounds in <i>Curcuma longa</i> as an Anticancer
by: Selliana Maretha Wijaya Kusuma, et al.
Published: (2022-11-01)

Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway
by: Yan Luo, et al.
Published: (2024-03-01)

To Investigate the Occurrence and Development of Colorectal Cancer Based on the PI3K/AKT/mTOR Signaling Pathway
by: Jiateng Zhong, et al.
Published: (2023-02-01)

Ropivacaine inhibits wound healing by suppressing the proliferation and migration of keratinocytes via the PI3K/AKT/mTOR Pathway
by: Xiaoyang Wu, et al.
Published: (2022-04-01)

A comprehensive view on the apigenin impact on colorectal cancer: Focusing on cellular and molecular mechanisms
by: Siamak Daneshvar, et al.
Published: (2023-11-01)

Activation of the PI3K-AKT-mTOR cascade in uterine leiomyosarcoma: a retrospective study of 31 patients
by: Olga A. Rozonova, et al.
Published: (2021-12-01)

Cerebral ischemia reperfusion injury: from public health perspectives to mechanisms
by: Gulnara Kapanova, et al.
Published: (2022-11-01)

Identification of ginsenoside components from adventitious root of ginseng and their hypoglycemic effects on T1DM mice: A network pharmacology and animal experiment study
by: Bin Xu, et al.
Published: (2024-05-01)

Effect and Mechanism of Ganoderma lucidum Spores on Alleviation of Diabetic Cardiomyopathy in a Pilot in vivo Study
by: Shaher F, et al.
Published: (2020-12-01)

Uncovering the mechanism of Kang-ai injection for treating intrahepatic cholangiocarcinoma based on network pharmacology, molecular docking, and in vitro validation
by: Fei Song, et al.
Published: (2023-03-01)

Intracellular Pathways and Mechanisms of Colored Secondary Metabolites in Cancer Therapy
by: Ani-Simona Sevastre, et al.
Published: (2022-09-01)

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
by: Antonino Glaviano, et al.
Published: (2023-08-01)

Targeting Akt/PKB in pediatric tumors: A review from preclinical to clinical trials
by: Bruno Toson, et al.
Published: (2022-09-01)

An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Zuogui Jiangtang Shuxin Formula in Diabetic Cardiomyopathy
by: Huang Y, et al.
Published: (2023-01-01)

Design, synthesis and anticancer activity studies of 3-(coumarin-3-yl)-acrolein derivatives: Evidenced by integrating network pharmacology and vitro assay
by: Lexian Chen, et al.
Published: (2023-03-01)

Integrated network pharmacology and experimental verification to investigate the mechanisms of YYFZBJS against colorectal cancer via CDK1/PI3K/Akt signaling
by: Jinxiao Li, et al.
Published: (2022-11-01)

Autophagy—A Hidden but Important Actor on Oral Cancer Scene
by: Totan Alexandra, et al.
Published: (2020-12-01)

Metformin Attenuates UVA-Induced Skin Photoaging by Suppressing Mitophagy and the PI3K/AKT/mTOR Pathway
by: Qiuyan Chen, et al.
Published: (2022-06-01)

Upregulation of CENPM facilitates lung adenocarcinoma progression via PI3K/AKT/mTOR signaling pathway
by: Liu Chao, et al.
Published: (2021-12-01)

Artesunate improves DDC-induced cholestatic liver fibrosis through PI3K/Akt/mTOR signaling pathway in mice
by: TANG Wan, et al.
Published: (2023-05-01)

Baicalin improves podocyte injury in rats with diabetic nephropathy by inhibiting PI3K/Akt/mTOR signaling pathway
by: Ou Yi, et al.
Published: (2021-09-01)

MGST1 alleviates the oxidative stress of trophoblast cells induced by hypoxia/reoxygenation and promotes cell proliferation, migration, and invasion by activating the PI3K/AKT/mTOR pathway
by: Dai Hu, et al.
Published: (2022-12-01)

Integrating network pharmacology and experimental validation to explore the effect and mechanism of AD-1 in the treatment of colorectal cancer
by: Jiawei Li, et al.
Published: (2023-05-01)

Molecular mechanism of polygonum multiflorum in the treatment of androgenic alopecia: based on bioinformatics and molecular docking method
by: Dongyu CHEN, et al.
Published: (2022-04-01)

The Importance of the PI3K/AKT/MTOR Pathway in the Progression of Ovarian Cancer
by: Charles N. Landen, et al.
Published: (2013-04-01)

Network pharmacology-based approach to investigate the molecular targets of essential oil obtained from lavender for treating breast cancer
by: Guzhalinuer Maitisha, et al.
Published: (2023-11-01)

The pathogenicity of vancomycin-resistant Enterococcus faecalis to colon cancer cells
by: Li Zhang, et al.
Published: (2024-02-01)

Study on the mechanism of Lu’an GuaPian tea in treating heart failure based on network pharmacology and molecular docking
by: Fang Hua, et al.
Published: (2023-12-01)

Mechanisms of Bushenyiqi decoction in the treatment of asthma: an investigation based on network pharmacology with experimental validation
by: Ziwen Qin, et al.
Published: (2024-03-01)

Investigation of the Mechanisms and Experimental Verification of Yulin Formula in the Treatment of Diminished Ovarian Reserve via Network Pharmacology
by: Wang R, et al.
Published: (2023-07-01)