Immunogenetic Factors Affecting Susceptibility of Humans and Rodents to Hantaviruses and the Clinical Course of Hantaviral Disease in Humans

Immunogenetic Factors Affecting Susceptibility of Humans and Rodents to Hantaviruses and the Clinical Course of Hantaviral Disease in Humans

We reviewed the associations of immunity-related genes with susceptibility of humans and rodents to hantaviruses, and with severity of hantaviral diseases in humans. Several class I and class II HLA haplotypes were linked with severe or benign hantavirus infections, and these haplotypes varied among...

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Bibliographic Details
Main Authors: Nathalie Charbonnel, Marie Pagès, Tarja Sironen, Heikki Henttonen, Olli Vapalahti, Jukka Mustonen, Antti Vaheri
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Viruses
Subjects:
hantavirus
Puumala virus
interaction
hosts
reservoirs
rodents
immunity-related genes
Online Access:http://www.mdpi.com/1999-4915/6/5/2214

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