| Summary: | The airborne microbiome is one of the relevant topics in ecology, biogeochemistry, environment, and human health. Bioaerosols are ubiquitous air pollutants that play a vital role in the linking of the ecosystem with the biosphere, atmosphere, climate, and public health. However, the sources, abundance, composition, properties, and atmospheric transport mechanisms of bioaerosols are not clearly understood. To screen the effects of climate change on aerosol microbial composition and its consequences for human health, it is first essential to develop standards that recognize the existing microbial components and how they vary naturally. Bioaerosol particles can be considered an information-rich unit comprising diverse cellular and protein materials emitted by humans, animals, and plants. Hence, no single standard technique can satisfactorily extract the required information about bioaerosols. To account for these issues, metagenomics, mass spectrometry, and biological and chemical analyses can be combined with climatic studies to understand the physical and biological relationships among bioaerosols. This can be achieved by strengthening interdisciplinary teamwork in biology, chemistry, earth science, and life sciences and by sharing knowledge and expertise globally. Thus, the coupled use of various advanced analytical approaches is the ultimate key to opening up the biological treasure that lies in the environment.
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